The Department of Chemistry offers MPhil programs designed to provide advanced training in modern chemical sciences while addressing Ghana’s industrial and research needs. The programs emphasize core chemical principles, advanced practical skills, independent research, and professional development in areas such as ethics, sustainability, and environmental responsibility.
Credit Hours - 3
The course covers the chemical nature of the key pollutants of air, soils and freshwater and marine bodies, the effects of the pollutants in the environment and management of the pollutants. The chemistry of the major industries, and their problems in relation to the environment and the alternatives
Credit Hours - 3
Measurement and instrumentation; resolution, sensitivity, selectivity, detection limit; sample pre-treatment techniques; detailed, consideration and applications of some selected methods e.g. AAS, AES, IR, UV, NMR, GC, GC-MS, HPLC, XRF, NAA etc.
Credit Hours - 3
The general methods for preparing the organometallic compounds of the Main Group (Groups IA, IIA IIIA, and IVA) elements and those of the d-transition elements. The important physical the chemical properties are discussed. Application of spectroscopic methods in determining the structure, including the nature of bonding between the metal and certain Organometallic compounds as intermediates in organic synthesis.
Credit Hours - 3
Introduction to Radiochemistry; Types of Radioactive decay; Nuclear Chemistry and Mass Energy Relationships, Nuclear Reactions; Rates of nuclear decay; Interaction of Radiation with Matter, Radioisotope production and availability, Radiotracer Methods; Uses of large radiation sources; Nuclear Activation Analysis; Principles of Activation Analysis; Prompt-Gamma Neutron Activation Analysis (PONAA) and Charged Particle Activation Analysis (CPNAA); Health Physics, Radiation Chemistry.
Credit Hours - 3
For year 2, each student will make a presentation soon after the Year I examinations on his/her Thesis Research Proposal and also present a progress report midway into the second semester. These will be assessed for 3 credits.
Credit Hours - 3
The structure and chemistry of sterols, bile acids, sex hormones, adrenal cortex hormones, steroidal glycoside, and alkaloids. Wherever necessary, the use of spectroscopic methods in the elucidation of structures, conformational analyses and the use of molecular rotation values, optical rotatory dispersion curve, and the octant rule to determine conformations.
Credit Hours - 3
Occurrence; isolation; general survey of the classes of terpenes; application of spectroscopic methods, degradative methods, synthetic methods and conformational analysis in structure elucidation; biosynthesis.
Credit Hours - 3
Topics to be treated each year will be selected from the following: Further Pharmacokinetics. The Kinetics of drug absorption and Elimination; The Plateau Principle; first order absorption and elimination; kinetics of drugs administered by inhalation.
Chemistry and Pharmacology of Selected Drug Types: The Receptor Concept; types of receptors; definitions of agonist; partial agonist antagonist; metagonist; ED50; IC50; pD2 and pA2 Antimalarials, Anti hypertensives including b-blockers. Non-steroidal anti-inflammatory drugs (NSAID); Chemical Carcinogens and Anti-cancer drugs. Vitamins Radiopharmaceuticals – preparation and application. Selected Physiochemical Methods of Drug Analysis; Bioassay methods, Fluorimetry, HPLC, Radio-immunoassays, Thermal methods. Principles of Drugs Quality Control: Quality assurance and Good Manufacturing Practices Definition of essential terms. Philosophy and Essential Elements of Quality Management.
Credit Hours - 3
Occurrence, isolation, general survey of the classes of alkaloids, application of spectroscopic methods, degradative methods, synthetic methods and conformational analysis in structure elucidation; biosynthesis.
Credit Hours - 3
Pre-requisite: CHEM 431 (2 credits) or evidence of having done an equivalent course at the undergraduate level. Electronic spin resonance spectroscopy; multi-pulse techniques in two dimensional NMR spectroscopy and their application to structure elucidation; NMR of nuclei like N-15, P-31 and F-19, biological NMR, ionisation techniques in mass spectroscopy other than electron impact
Credit Hours - 3
The objective of this course is three fold: To equip the graduate with the necessary theoretical tools to enable the student formulate reasonable synthetic schemes for complex organic molecules. To enable the student read and understand articles in journals on synthesis of organic molecules. To be able to bring all elements of Organic Chemistry (mechanisms, stereochemistry and strategy) to bear on synthesis. In the first part of the course a review of the major reactions in organic synthesis will be done. In the second part some selected organic molecules will be taken from current literature and the synthetic schemes will be discussed. The selection of the molecules to be discussed will be done in such a way that the student will be exposed to almost all the major reactions in organic synthesis. Finally the student will be given one selected synthetic organic chemistry topic to review and present as a theoretical project.
Credit Hours - 3
In year 1, each student in a Department or Programme is expected to attend all seminars specified
and make his/her own presentation on selected topics to an audience. Each student will be expected to make at least one oral presentation to be assessed each semester and also present a full write-up of the presentation for another assessment. These will earn a total of 3 credits.
Credit Hours - 3
A study of the laws and theory of Photochemistry. Topics include: the theory of the excited state, electronic spectra of excited state, transients and their behaviour, experiments techniques, photochemical processes in the gas phase, mechanisms of organic photochemical reactions, photochromism, and industrial application. Laboratory experiments give practical experience to the theory covered in class.
Credit Hours - 3
Pre-requisite: Quantum Chemistry Experimental arrangement for observing atomic spectra Units in atomic spectroscopy General structures of spectrum. The hydrogen atoms. Outline of solutions of the wave equation and expressions for energies. Wave Mechanical Approach. Energy level 51 Diagram of Hydrogen and Spectrum. Relatively and fine structure of lines. Alkali spectra and more complex structure.. Elusion collision experiments; Many electron atoms. Terms symbols, Multiplicity of terms. Zeeman and Paschen-Back effects. Intensity of spectral lines. Elementary Chemical processes and excited states. Collisions of the first and second kinds.