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BCMB 305: Biochemistry Of Hormones

Credits: 
2

General introduction: Coordination in multicellular organisms
Major classes of hormones: Mammalian, plants, insects.
Major endocrine glands: Hypothalamus, pituitary, adrenals, testes, ovaries, pancreas.
Biosynthesis and degradation of hormones: regulation of synthesis/secretion; major biochemical effects and actions. Hormone receptors: structure, relationship to binding to response, binding characteristics, segregation, auto-phosphorylation/cross-phosphorylation; internalization.
Types of post receptor mechanism: second messenger generation, hormone response elements, gene expression.