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Tagoe Emmanuel Ayitey (BSc, MPhil, PhD)

Tagoe Emmanuel Ayitey (BSc, MPhil, PhD)
Senior Lecturer
eatagoe@ug.edu.gh / eatagoe@chs.edu.gh / eatagoe16@gmail.com
0277184677 / 0206269962

RESEARCH INTEREST                  

Tagoe’s Lab focuses on the mechanistic role of pathogens in the aetiology of non-communicable diseases including cancers. Well-established molecular tools and bioinformatics are used to investigate virulent diversity of pathogens, and how pathogens and/or their oncoproteins disrupt host signalling to cause diseases. The lab also studies metabolic reprogramming especially in cancers- in all identifying biomarkers for diagnosis and potential therapeutic targets.

 

SELECTED PUBLICATIONS

  1. Santa S, Doku DA, Olwal, CO, Brown CA, Tagoe EA.  Quaye O. (2022). Paradox of COVID-19 in pregnancy: are pregnant women more protected against or at elevated risk of severe COVID-19? Future Microbiology, 17(10):803-812.
     
  2. Adusei E, Ahenkorah J, Adu-aryee NA, Adutwum-ofosu KK., Tagoe EA, Koney NK., Nkansah E, Aryee NA, Blay RM, Hottor BA, & Arko-Boham B. (2021). Reduced Serum Circulation of Cell-Free DNA Following Chemotherapy in Breast Cancer Patients. Medical Sciences, 9:37–46.

 

  1. Tagoe EA, Awandare GA, Quaye O, Asmah RH, Archampong TN, Osman MA, Brown CA. Helicobacter pylori variants with ABC-Type tyrosine phosphorylation motif in gastric biopsies of Ghanaian patients. Biomed Res Int. 2021;2021:1–7.

 

  1. Tagoe EA, Dwamena-Akoto E, Nsaful J, Aikins AR,, Clegg-Lamptey J-N,  Quaye O. High atherogenic index of plasma and cardiovascular risk factors among Ghanaian breast cancer patients. Experimental Biology and Medicine. 2020; 0: 1–8.

 

 

  1. Ayee R,  Ofori, MEO, Tagoe EA,  Languon, S,  Searyoh K, Armooh L,  Bilson-Amoah E, Baidoo K, Kitcher E,  Wright E, Quaye O. Genotypic Characterization of Epstein Barr Virus in Blood of Patients with Suspected Nasopharyngeal Carcinoma in Ghana. Viruses. 2020; 12(7): 766.

 

  1. Arko-Boham B, Owusu, BA, Ayite Aryee, NA, Blay RM, Owusu, EDA, Tagoe EA, Adams AR, Gyasi RK, Adu-Aryee, NA, and Seidu Mahmood S. Prospecting for Breast Cancer Blood Biomarkers: Death-Associated Protein Kinase 1 (DAPK1) as a Potential Candidate. Disease Markers. 2020: 2020; 1-7.

 

  1. Tagoe EA, Tagoe INA, Kuleape JA, Puplampu P, Amanquah S, Asare-Anane H,  Quaye O. Haptoglobin phenotypes with weak antioxidant capacity increase risk factors of cardiovascular disease in Ghanaian HIV-infected patients on highly active antiretroviral therapy. Tropical Medicine and International Health. 2019; 24(6): 766–774.

 

  1. Quaye O, Kuleape JA, Bonney EY, Puplampu P, Tagoe EA.  Imbalance of antioxidant enzymes activities and trace elements levels in Ghanaian HIV infected patients. PLoS ONE. 2019; 14(7): e022018.

 

  1. Quaye O, Amuzu BG, Adadey SM, Tagoe EA. Effect of Hepatitis B Virus (HBV) Infection on Lipid Profile in Ghanaian Patients. Virology: Research and Treatment. 2019: 10:1-5.       

 

  1. Arko-Boham B, Aryee, NA Owusu, BA, Blay RM, Owusu, EDA, Tagoe EA, Shackie ESD, Debrah AB, Adu-Aryee NA.  Circulating cell-free DNA integrity as a diagnostic and prognostic marker for breast and prostate cancers. Cancer Genetics. 2019; 235 (236): 65–71.

 

  1.  Kuleape JA, Tagoe EA, Puplampu P, Bonney EY, Quaye O. Homozygous deletion of both GSTM1 and GSTT1 genes is associated with higher CD4+ T cell counts in Ghanaian HIV patients. PLoS ONE. 2018; 13(5): e0195954.

 

  1. Tagoe EA, Arko-Boham B, Adjorogbe B, Aryee NA, Quaye O, Samuel M. Adadey SM, Clegg-Lamptey J-N. Glutathione S-Transferase T1 and M1 Gene Polymorphisms among Breast Cancer Susceptible Ghanaians. Clin. Invest. (Lond.). 2017; 7(2):119-125.

 

  1. Osman MA, Bloom GS, Tagoe EA. Helicobacter pylori-Induced Alteration of Epithelial Cell Signaling and Polarity: A Possible Mechanism of Gastric Carcinoma Etiology and Disparity. Cytoskeleton. 2013; 70:349–359.