Dr. Nicholas Israel Nii-Trebi (PhD)

Dr. Nicholas Israel Nii-Trebi is a Snr. Lecturer with the Department of Medical Laboratory Sciences, School of Biomedical and Allied Health Sciences of the College of Health Sciences, Uiversity of Ghana. Dr. Nii-Trebi obtained his Bachelor and Master degrees at the University of Ghana, and had his PhD degree in Medical Science from the Kumamoto University.Japan. His teaching focuses on virus architecture, basic concepts in virology and viral diagnostics, and virus-host interactions. His research focus is to advance understanding of virus behaviour, genetic diversity of viruses including HIV, HCV and SARS-CoV-2, and the role of host genetic in outcome of viral infections in Ghanaians. His current research themes encompass deciphering the HCV genome organization and species diversity in Ghana; HIV drug resistance, species diversity and host factors in HIV outcomes, and SARS-CoV-2 phylodynamics, molecular epidemiology as well as host genetics in COVID-19 outcomes in Ghanaians.

Selected Publications

Nii-Trebi NI, Matsuoka S, Kawana-Tachikawa A, Bonney EY, Abana CZ, Ofori SB, et al. (2022) Super high-resolution single-molecule sequence-based typing of HLA class I alleles in HIV-1 infected individuals in Ghana. PLoS ONE 17(6): e0269390. https://doi.org/10.1371/journal.pone.0269390

Okoh, O.S., Nii-Trebi, N.I., Jakkari, A., Olaniran, T.T., Senbadejo, T.Y., Kafintu-kwashie, A.A., Dairo, E.O., Ganiyu, T.O., Akaninyene, I.E., Ezediuno, L.O., Adeosun, I.J., Ockiya, M.A., Jimah, E.M., Spiro, D.J., Oladipo, E.K., Trovão, N.S., Epidemiology and genetic diversity of SARS-CoV-2 lineages circulating in Africa, ISCIENCE (2022), doi: https://doi.org/10.1016/j.isci.2022.103880.

Nicholas Israel Nii-Trebi, Charles Addoquaye Brown1, Yaa Difie Osei, William Kwabena Ampofo and Alexander Kwadwo Nyarko. Core encoding sequences of Hepatitis C virus in Ghanaian blood donors are predominantly mosaics of different genotype 2 strains and cannot distinguish subtypes. BMC Infectious Diseases 2019; 19:533.

Mildred A. Adusei-Poku1, Saori Matsuoka, Evelyn Y. Bonney, Christopher Z. Abana, Ewurabena O. Duker, Nicholas I. Nii-Trebi, et al. Human leukocyte antigen-associated HIV-1 CRF02_AG gag and vif polymorphisms in Ghana. Japanese Journal of Infectious Diseases (JJID)

Nicholas Israel Nii-Trebi et al., Dynamic HIV-1 genetic recombination and genotypic drug resistance among treatment-experienced adults in northern Ghana. J Med Microbiol 2017; 66:1663–1672. DOI 10.1099/jmm.0.000621

Nicholas Israel Nii-Trebi. Emerging and Neglected Infectious Diseases: Insights, Advances, and Challenges. BioMed Research International, vol. 2017 (2017), Article ID 5245021, https://doi.org/10.1155/2017/5245021.