Credit Hours - 6

Objective

The objective of the project is to give the student an independent problem-solving experience where the candidate identifies a biomedical problem from the healthcare sector or industry and devise strategies to address the problem.

Content

The course requires review of literature, and preparation of a long essay paper. Other emerging technologies that are currently utilized in the field to tackle biomedical problems can be applied in solving local problems. Regular progress reports and meetings with a faculty advisor are requirement for this course.

Credit Hours - 3

Objective

The objective of this course is to train students on the methods and applications of biomedical engineering in healthcare delivery. 

Content

Topics to be taught include but not limited to understanding the different signal processing and instrumentation; biomechanics; biomaterials science and selected emerging topics in regenerative engineering applications; medical and engineering ethics; stem cells growth and maintenance. Membrane structure and morphology as well as scaffolding in regenerative engineering.

Reading List

• Abu-Faraj, Z. a (2012). Handbook of Research on Biomedical Engineering Education and Advanced Bioengineering Learning: Interdisciplinary Cases. Hershey: Medical. Information Science Reference.
• Coh, G. E. (2004). Advanced Biomedical and Clinical Diagnostic Systems II. In Proceedings of Spie (Vol. 2).
• Enderle, J., & Bronzino. (2011). Introduction to Biomedical Engineering. London: Academic Press.
• Enderle, D. J., & Joseph, D. (2005). Introduction to Biomedical Engineering. London: Academic Press
• Gargiulo, G. D. (2011). Advanced Biomedical Engineering. London: Academic Press.
• Lee, J. K., Responte, D. J., Cissell, D. D., Hu, J. C., Nolta, J. A., & Athanasiou, K. A. (2013). Clinical translation of stem cells: insight for cartilage therapies. Critical Review Biotechnology.
• Griffith, L. G., & Grodzinsky, A. J. (2001). Advances in Biomedical Engineering. The Journal of the American Medical Association, 285,556-56.

Credit Hours - 4

Objective

The objective of this course is to introduce students to the key principles of regenerative engineering. This course covers fundamental topics in tissue engineering and regenerative medicine, specifically application of engineering principles to the design and fabrication of functional tissues and organs.

Content

Topics taught in this course are Tissue Exchange and Tissue Development, Elements of Tissue development. Cell growth and differentiation, Cell and tissue mechanism, cell adhesion, cell migration, cell aggregation and tissue equivalent. Regenerative medicine such as stem cell-based therapy, scaffold design, proteins or genes delivery, roles of extracellular matrix, cell- materials interactions, angiogenesis, tissue transplantation, mechanical stimulus and nanotechnology.

Reading List

• Geuna, S., Gnavi, S., Perroteau, I., Tos, P., & Battiston, B. (2013). Tissue Engineering and Peripheral Nerve Reconstruction: An Overview. International Review Neurobiology, 108C, 35-57.
• Hay, D. (2012). Regenerative Medicine, Stein Cell and the Liver. London: Science Publishers. IEEE Transactions on Biomedical Engineering. IEEE Explore Digital Library
• Laurencin, C. T., & Khan, Y. (2013). Regenerative Engineering. London: CRC Press.
• Saltzman, W. M. (2004). Tissue Engineering — Engineering principles for design of replacement organs and tissue. USA: Oxford University Press.
• Stocum, D. L. (2006). Regenerative Biology and Medicine. London: Academic Press.
• Wnek, G. E., & Browlin, G. L. (2004). Encyclopaedia of Biomaterials and Biomedical    Engineering. Durham: Marcel Dekker Inc.

Credit Hours - 4

Objective

This objective of this course is to teach some special topics to students who desire to pursue investigations in specialized fields in nanofabrication to advance research in life sciences and the biology to create new micro- and nanoscale devices to better understand life processes at the nanoscale will be taught.

Content

Various experimental methods of production, characterization and analysis of metallic nanoparticles and their applications to medicine would be discussed.

Reading List

• Jain, K. K. (2008). The Handbook of Nanomedicine. New York: Humana Press.
• Niemeyer, C. M., & Mirkin, C. A. (2004). Nanobiotechnolgy: Concepts, Applications and Perspective. New Jersey: Wiley-VCH.
• Ng, S. H., Woi, P. M., Basri, M., & Ismail, Z. (2013). Characterization of structural stability of palm oil esters-based nanocosmecaiticals loaded with tocotrienol. Journal of Nanobiotechnology, I I, 1— 7.
• Prasad, P. N. (2012). Introduction to Nanomedicine and Nanobioengineering. New Jersey: Wiley.
• Rosenthal, S. J., & Wright, D. (2005). Nanobiotechnolgy Protocols. New York: Humana Press. The Institute of Electrical and Electronics Engineers Transactions on Nanotechnology.IEEE Xplore: Digital Library.
• The Institute of Electrical and Electronics EngineersNanobiotechnology, IEEE Proceedings. IEEE Xplore: Digital Library.

Credit Hours - 3

Objective

The objective of this biomedical devices fabrication course is to expose to students, the field of devices fabrication from the biomedical engineering point of view, the value of application of devices to targeted drug delivery, efficacy of therapy and in public health. 

Content

Topics such as materials selection and design, degradability and non-degradability of implants, biocompatibility and testing will be taught. Topics to be studied by the students include the material characterization and changes in the physiological environment both from the biomaterial and the physiological perspective.

Reading List

• Kucklick, T. R. (2012). The Medical Device R&D Handbook. London: CRC Press.
• Karaglciozaki, V., Karagiannidis, P. G., Gioti, M., Kavatzikidou, P., Georgiou, D., Georgaraki, E., & Logothetidis, S. (2013). Bioelectronics meets nanomedicine for cardiovascular implants: PEDOT-based nanocoatings for tissue regeneration. Biochimie. Biophysica. Acta, 1830,4294-4304. IEEE Transactions on Biomedical Engineering
• Girins, H. (2012). The fabrication of a complex implant-supported restoration. Boston: DIG Dental Publishing.
• Moore, J. E. J., & Duncan, J. (2013). Biomedical Technology and Devices. London: CRC Press. Shellock, F. G. (2013). Reference Manual for Magnetic Resonance Safety, Implants, and Devices. London: Biomedical Research Publishing Group.
• Shulz, M. J., Sjanov, V. N., & Yun, Y. (2009). Nanomedicine Design of Particles, Sensors, Motors, Implants, Robots, and Devices. Ghana: Artech House Publishers.
• Zinner, I. D., -Markovits, S., Jansen, C. E., Reid, P. E., Schnader, Y. E., & Shairo, J. H. (2012).
• Sequential provisional implant prosthodontics therapy. Genteronlogy Denturist, 60, 508­18.

Credit Hours - 4

Objective

To bring students to the level where their understanding of cell and molecular biology will allow them to appreciate tissue engineering concepts.

Content

This course seeks to explain the similarity of genetic materials in cells and how each cell is different based on the composition of expressed protein. In this course, we will discuss major topics in gene expression including transcription and transcription-coupled processes in eukaryotes. We will discuss key concepts in RNA synthesis and the role of chromatin and noncoding DNA in regulating gene expression. The structure and function of nucleic acids as applied to the storage, replication, recombination, and processing of biological information will be discussed. We shall also explore macromolecular structure, function and dynamics of protein and RNA molecules.

Reading List

• Alberts, B., Johnson, A., Lewis, J., & Raff, M. (2007). Molecular Cell Biology. New York: Garland Science.
• Berk, A., Kaiser, C. A., Krieger, M., Bretscher, A., Ploegh, H., Amon, A., Lodish, H. (2012). Molecular Cell Biology. New York: W. H. Freeman.
• Mclane, J. S., Schaub, N. J., Gilbert, R. J., & Ligon, L. A. (2013). Electrospun nanofiber scaffolds for investigating cell-matrix adhesion. Methods Molecular Biology, 1046:371-388
• Slack, J. M. W. (2012). Essential Developmental Biology. New Jersey: Wiley-Blackwell.
• Wilson, J., & Hunt, T. (2007). Molecular Biology of the Cell, Fifth Edition: The Problems Book. New York: W. H. Freeman.
• Yang, Z., Hai, B., Qin, L., Ti, X., Shangguan, L., Zhao, Y., Liu, F. (2013). Cessation of epithelial Bnip signaling switches the differentiation of crown epithelia to the root lineage in a 13-catenin-dependent manner. Molecular Cell Biology.

Credit Hours - 3

Objective

The objective of this course is to provide an examination of technology and its impact on medicine, with emphasis on the intersection of engineering with medicine and health. 

Content

Basic foundations of historical perspective, constraints on technological development in medicine will be discussed. Planned topics include drug development and pipelines, hospital technology management, implants with emphasis on medical devices other novel rehabilitative devices. (Diagnostics engineering, therapeutic engineering, monitoring device engineering, rehabilitation engineering)

Reading List

• Anasta M. A., & La Riviere, P. (2012). Emerging Imaging Technologies in Medicine. London: Taylor & Francis.
• Engineering and Public Policy Committee on Science, institute of Medicine, Policy and Global Affairs, National Academy of Science. (2009). On Being a Scientist: A Guide to Responsible Conduct in Research. Washington: National Academies Press.
• Fong, A. C. M., & Li, C. K. (2010). Telemedicine Technologies: Information Technologies in Medicine and Telehealth. New Jersey: Wiley. IEEE Explore Digital Library
• Miller, G. E. (2006). Sensory Organ Replacement and Repair. California: Morgan and Claypool Publishers.
• Oya, I-I., Howard, M. A., Shurig, R., & Gilles, G. T. (2012). Spinal canal surrogate for testing intradural implants. Tissue Engineering, Part A, 36, 407-410.
• Saltzman, W. M. (2009). Biomedical Engineering: Bridging Medicine and Technology. Cambridge: Cambridge University Press.

Credit Hours - 3

Objective

The objective of the seminar is to have students review research literature and select long essay type projects of interest in biomedical engineering, prepare and give presentations. A faculty guide is to be allotted and he/she will guide and monitor the progress of the student and maintain attendance. Students are encouraged to use various teaching aids such as overhead projectors, PowerPoint presentations and demonstrative models. This will enable them to gain confidence in facing placement interviews.

Reading List

• Chambers, H. E. (2000). Effective Communication Skills for Scientific and Technical Professionals Paperback. New York: Basic Books.
• Cohen, W. A. (2001). How to Make It Big as a Consultant. London: AMACOM.
• Jolles, R. L. (2005). How to Run Seminars & Workshops: Presentation Skills for Consultants, Trainers and Teachers Paperback. New Jersey: Wiley.
• Kahrs, T. K. (2009). Presentation Skills Mastery. CreateSpace.
• Maselli, F. (2002). Seminars: The Emotional Dynamic—Advanced Presentation Skills for Financial Professionals. London: Creative Image.
• Robson, C. (2002). Real World Research: A Resource for Social Scientists and Practitioners.
• Sony. (2000). Professional Training for Vegas 6 Software. Sony Media SoftSTV2000.

Credit Hours - 4

Objective

This course will discuss the fundamentals of bio-MEMS, micro-structures, micro-fluidics, micro-sensors and micro-actuators.

Content

MEMS and microsystems: Working principle of Microsystems, materials for MEMS and Microsystems, micromachining, System modeling and properties of materials. Mechanical sensors and actuators — beam and cantilever, piezoelectric materials, thermal sensors and actuators- micromachined thermocouple probe, Peltier effect heat pumps, thermal flow sensors, Magnetic sensors and actuators- Magnetic Materials for MEMS, Devices. BioMEMS: Drug delivery, micro total analysis systems (microtas), detection and measurement methods, microsystem approaches to polymerase chain reaction (PCR), DNA hybridization, electronic nose, Biochip.

Reading List

• Badilescu, S., & Packirisamy, M. (2011). BioMEMS: Science and Engineering Perspectives. London: CRC Press.
• Barkam, S., Saraf, S., & Seal, S. (2013). Fabricated Micro-Nano Devices for In vivo and In vitro Biomedical Applications. Wiley Interdisciplinary Review Nanomedicine Nanobiotechnology, 5,544-568.
• Folch, A. (2012). Introduction to BioMEMS. London: CRC Press.
• Hsu, T. R. (2002). MEMS and Microsystems design and manufacture. Digital Book. Mahalik, N. P. (2007). MEMS. India: Tata McGraw-Hill Education.
• Wang, W., & Soper, S. A. (2007). BioMEMS- Technologies and applications. Boca Raton: CRC Press.

Credit Hours - 4

Objective

This course would equip students to apply structural biology concepts to analyse protein structures and function.

Content

Molecular aspects and dynamics of structural biochemistry, examination of nucleic acid, protein, and lipid structures including current topics in conformation and folding, enzyme kinetics, nucleic acid stability, ligand/receptor binding, and bioenergetics. Explanation of experimental strategies including x-ray crystallography, electron microscopy, magnetic resonance and electron paramagnetic spectroscopies used to study macromolecular structure and function.

Reading List

• Berliner, L. J., & Reuben, J. (1992). Biological Magnetic Resonance. New York: Plenum Press.
• Likhtenshien, G. I. (1993). Biophysical Labeling Methods in Molecular Biology. London: Cambridge University.
• Tiburu, E. K., Bass, C. E., Struppe, J. 4., Lorigan, G. A., & Avraham, H. K. (2007). Structural divergence among cannabinoids influences membrane dynamics: a 2H solid-state NMR analysis. BiochimieBiophysica Acta, 1768,2049-2059.
• Tiburu, E. K., Gulla, S. V., Tiburu, M., Janero, D. R., Budil, D. E., & Makriyannis, A. (2009). Dynamic conformational responses of a human cannabinoid receptor-1 helix domain to its membrane environment. Biochemistry, 48,4895-4904.
• Weil, J. A., Bolton, J. R., & Wertz, J. E. (1993). Electron Paramagnetic Resonance: Elementary Theory and Practical Applications. USA: Wiley.

Credit Hours - 3

Objective

The objective of this course is to introduce students to relevant methodologies and software employed in the acquisition and analysis of biological data and develop hands-on experience in the use of these tools. Students would analyse biomedical data pertaining to infectious and tropical diseases.

Content

Introduction to genomics, proteomics, microarray, molecular evolution and phylogenetics, metabolomics, drug discovery, protein-protein interactions, pathway and network analysis, biomedical text and data mining. Students will be taught how to use computational and statistical methods for the modelling and analysis of all kinds of biological data, as well as other areas of computational biology.

Reading List

• Baxevanis, A. D., & Oulette, B. F. F. (2001). Bioinformatics: A practical Guide to the analysis of Genes and Proteins. New Jersey: Wiley-Interscience.
• Buggenthin, F., Marr, C., Schwarzfischer, M., Hoppe, P. S., Hilsenbeck, 0., Schroeder, T., & Theis, F. J. (2013). An automatic method for robust and fast cell detection in bright field images from high-throughput microscopy. Bioinformatics, BMC.14:297-308.
• Haddock, S., & Dunn, C. (2010). Practical Computating Biologists. Sunderland: Sinauer Associates.
• Kinser, J. (2009). Python For Bioinformatics: Jones and Bartlett Series in Biomedical Informatics. Wood Holes: Jones & Bartlett.
• Pevsner, J. (2009). Bioinformatics and Functional Genomics. New Jersey: Wiley Blackwell.

Credit Hours - 4

Objective

To introduce students to principles for modelling physiological systems and processes of the human body.

Content

Unified study of engineering techniques and basic principles in modeling physiological systems. Focuses on membrane biophysics, biological modeling, and systems control theory. Significant engineering and software design is incorporated in homework assignments using MATLAB, SIMULINK, Cytoscape and any other essential software packages.

Reading List

• Ambrosi, D., Quarteroni, A., & Rozza, G. (2011). Modeling of Physiological Flows (MS&A). Berlin: Springer.
• Devasahayarn, S. R. (2000). Signals and Systems in Biomedical Engineering: Signal Processing and Physiological Systems Modeling: Topics in Biomedical Engineering. Berlin: Springer.
• Hafner, J. W. (2005). Modeling Biological Systems. Principles and Application. Berlin: Springer. Karris, S. T. (2006). Introduction to Simulink with Engineering Application. California: Orchard Publications.
• Marmarelis, V. Z. (2011). Nonlinear Dynamic Modeling of Physiological Systems (IEEE Press Series on Biomedical Engineering). New Jersey: Wiley-IEEE Press.
• Yokota, M., Berglund, L. G., & Xu, X. (2013). Thermoregulatory modeling use and application in the military workforce. Applied Ergonomics.
• (drug absorption, blood flow, cardiovascular modeling, drug modelling)****

Credit Hours - 4

Objective

The objective of this course is to introduce students to the theory and practice of biological modelling at the molecular to cellular level.

Content

Cellular response to drugs and toxins, as well 'as normal cell processes such as proliferation, growth and motility often involve receptor-ligand binding and subsequent intracellular processes. Student will use modeling tools by focusing on mathematical formulation of equations for key cellular events including binding of ligands with receptors on the cell surface trafficking cellular processes of the receptor-ligand complex within the cell and cell signaling by second messengers to predict cellular processes.

Reading List

• Boyd, D. W. (2000). System Analysis and Modeling: Macro-to-Micro Approach with Multidisciplinary Applications. Harcourt: Academic Press.
• Kretschmer, J., Godenschwager, C., Preim, B., & Stamminger, M. (2003). Interactive patient-specific vascular modeling with sweep surfaces. IEEE Trans Visual Computational Graph, 19,2828-2837.
• Lu, D. R., & Oie, S. (2004). Cellular Drug Delivery: Principles and Practice. New York: Humana Press.
• McNally, E. J., & Hastedt, J. E. (2007). Protein Formulation and Delivery (2nd ed.). New York: Humana Press.
• SIAM Journal of Multiscale Modelling and Simulation.

Credit Hours - 4

Objective

This course would teach students the basics of 3D geometric modelling. Students will gain an understanding of techniques for visualizing and rendering geometric models. 

Content

This course deals with mathematical modeling, computer representations and algorithms for manipulating geometry on a computer. It focuses on the basic concepts of solid and geometric modeling from geometry and topology and uses these concepts to develop computational techniques for creating, editing, rendering, analyzing and computing models of physical objects, mechanical parts, assembly and processes.

Reading List

• Deo, N. (1983). System Simulation with Digital Computer. India: Prentice Hall.
• Gordon, G. (1978). System Simulation. India: Prentice Hall.
• Garner, J. (1999). Curves and Surfaces in Geometric Modeling: Theory & Algorithms (The Morgan Kaufinann Series in Computer Graphics). Burlington: Morgan Kaufinann.
• Kretschmer, J,, Godenschwager, C., Preim, B., & Stamminger, M. (2003). Interactive patient-specific vascular modeling with sweep surfaces. IEEE Trans Visual Computational Graph, 19,2828-2837.
• Mortenson, M. (2006). Geometric Modeling. London: Industrial Press.
• Zeigler, B., Praehofer, H., & Kim, T. G. (2000). Theoly.of Modeling and Simulation.
• London: Academic Press.

Credit Hours - 4

Objective

The course is to introduce students to the principles for the design of instrumentation systems as applicable to physiology and explore the human body parameter measurements setups.

Content

Bioinstrumentation is an interdisciplinary field requiring knowledge of the principles in several areas including digital electronic systems, control systems and detection systems. Students will be trained on how to integrate the concepts and principles within the above areas to realize complete instrumentation systems with a variety of individual components, physics behind each application.

Reading List

• Bialek, W., (2012). Biophysics: Searching for Principles. New Jersy: Princeton University.
• Dirnitrov, G. V., Dimitrova N.A., & Pajeva, I. K., (1992). Threshold stimulation and accommodation of the Hodgkin-Huxley, axon. General Physiology Biophysics, 11, 59-68
• Dillon, P. F. (2012). Biophysics. A Physiological Approach. London: Cambridge.
• Enderle, D. J. (2006). Bioinstrumentation (Synthesis Lectures on Biomedical Engineering Synthesis Lecture). California: Morgan and Claypool.
• Liu, J., Hogan, N. C., & Hunter, I. W. (2012). Intradermal needle-free powdered drug injection by a helium-powered device. In IEEE Engineering Medical Biology Society.2012: 2068­2071 (pp. 2068-2071).
• Pethig, R. R., & Smith, S. (2012). Introductory Bioelectronics: For Engineers and Physical Scientists. New York: Wiley.
• Webster, J. G. (1994). Medical Instrumentation Application and Design. New Jersey: Wiley.

Credit Hours - 4

Objective

This course introduces students to concepts in the development devices used in a clinical or biological environment as well as the modes of operation of medical instrumentation systems.

Content

Analysis and design of transducers and signal processors; measurements of physical, chemical, biological, and physiological variables; special purpose medical instruments, systems design, storage and display, grounding, noise, and electrical safety. These concepts are considered in developing devices used in a clinical or biological environment. Generalized medical instrumentation system and their operational modes.

Reading List

• Avansino, J. R., Goldin, A. B., Risley, R., Waldhausen, J. H., & Sawin, R. S. (2013). Standardization of operative equipment reduces cost. Journal Pediatrics Surgery, 48, 1843-1849.
• Bishop, M. L. Edward, P., Fody, E. P., & Schoeff, L. E. (2013). Clinical Chemistry: Techniques, Principles, Correlations. North American: Lippincott Williams & Wilkins.
• Northrop, R. B. (2002). Noninvasive Instrumentation and Measurement in Medical Diagnosis. London: CRC Press.
• Prutchi, D., & Norris, M. (2005). Design and Development of Medical Electronic Instrumentation. New Jersey: Wiley-Interscience.
• Tobler, W. D., Melgar, M. A., Raley, T. J•, Anand, N., Miller, L. E, & Nasca, R. J. (2013).
• Clinical and radiographic outcomes with L4-S1 axial lumbar interbody fusion (AxiaLIF) and posterior instrumentation: a multicenter study. Medical Devices, 18,155-161

Credit Hours - 4

Objective

The objective of this course is to expand student knowledge on imaging technologies for biomedical applications. 

Content

Advanced techniques of ultrasonic image formation for biomedical applications. Acoustic wave propagation. A, B, C, M and Doppler ultrasonic imaging modes. Interaction of ultrasound with biological tissue. Acoustical holography. Ultrasonic transducer design and calibration. Transducer arrays. Ultrasound detection modes. Laboratory demonstrations will include Schieren visualization of ultrasound fields and transducer calibration techniques. Assumes a background in linear systems.

(This course  Should cover other areas of medical imaging, such as PET, SPECT, CT, MRI.  You may give special attention to UIT.)**

Reading List

• Bontrager, K., & Lampignano, J. (2013). Bontrager's Handbook of Radiographic Positioning and Techniques (8th ed.). New York: Mosby.
• Castera, L., Vilgrain, V., & Angulo, P. (2013). Noninvasive evaluation of NAFLD. Nature Review. Gastroenterology Hepatology, 175.
• Christof, M. D., Blohmer, S. J. & Hamper, U. (1999). Breast Ultrasound: A Systematic Approach to Technique and Image Interpretation. New York: George Thieme Verlag. Galasko, C. S. B., & Isherwood, I. (2011). Imaging Techniques in Orthopaedics. Berlin: Springer.
• Miller, D. J., & Skucas, J. (2011). The Radiological Examination of the Colon: Practical Diagnosis. Berlin: Springer.
• Skucas, J. (2006). Advanced Imaging of the Abdomen. Berlin: Springer.

Credit Hours - 4

Objective

This course would introduce students to optical methods and techniques used for imaging and other relevant biomedical applications.

Content

Vibrational spectroscopic technique that can probe specific biochemical and biomolecular changes associated with disease transformation will be taught. Raman spectroscopy and endoscopic imaging for improving the noninvasive, in vivo diagnosis and detection of cancer cells. Optical methods for noninvasive imaging of neural activation and brain function and different types of infectious agents.

Reading List

• Boas, D. A. Pitris, C., & Ramanujam, N. (2011). Handbook of Biomedical Optics. London: CR Press.
• Lihong, V., Wang, L.V., & Wu, H. (2007). Biomedical Optics: Principle and imaging. London: CRC Press
• Tuchin, V. V. (2002). Dictionary of Biomedical Optics and Biophotonics (Vol. PM217). London: CRC Press
• Tuchin, V. V. (2009). Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues. New York: Taylor & Francis.
• Shaked, N. T., Zalevsky, Z., & Satterwhite, L., (2012) Biomedical Optical Phase Microscopy and Nanoscopy. London: CRC Press.

Credit Hours - 45

Objective

The objective of this course is to train the student to acquire the skills necessary for employing specific systematic methods for acquiring research data and studying the data to derive outcomes that are valuable for addressing a given problem.

Content

The detail content depend on the topic of research, but it will generally include literature review, critical appraisals, gathering of research data/performing experiments, analyzing information gathered, presentations at conferences, thesis and other reports writing. The doctoral candidate will work under the supervision of a faculty member during which he/she is expected to conduct research on an original research project. Such work will either be added information to an existing work already published by other investigators or original idea developed by the candidate. The results generated will be synthesized and put in a dissertation. Some of the work must be submitted for publication before the student graduates. Periodic evaluation through seminars and individual contact with the approved supervisor will be made.

Reading list

• Bolker, J. (1998). Wrting Your Dissertation in fifteen minutes a Day: A Guide to Starting, Revising, and Finishing Your Doctoral Thesis [ Paperback]. Oxford: Owl Books.
• Campbell, D.T , and Stanley, J.C., (1990). Experimental and Quasi-Experimental Designs for Research. London. Cengage Learning 
• Davis, G.B., Parker, C.A., Straub, D.W.(2012). Writing the Doctoral Dissertation: A Systematic Approach[Paperback. New York: Baron’s Educational Series.
• Madsen, D.(1991). Successful Dissertations and Theses: A Guide to Graduate Student Research from Proposal to Completion. New York: Jossey- Bass
• Robson, C.(2002). Real World Research: A Resource for Social Scientists and Practitioners. New York: Wiley

Credit Hours - 3

Objective

This course would introduce the detailed concepts of scaffolds in regenerative engineering.

Content

The criteria for using different scaffolds in a variety of application areas would be discussed. This includes nano, micro and macro encapsulation of cells, in-situ polymerization and implantable gels, micro and microporous scaffolds in the delivery of bioactive molecules. The course will also cover some scaffold materials.

Reading list

• Binan, L., Ajji, A., De Crescenzo, G., Jolicoeur, M. (2013). Approaches for Neural Tissue Regeneration. Stem Cell Review.9,1558-6804.
• Laurencin, C. T., & Khan, Y. (2013). Regenerative Engineering. London: CRC Press.
• Lui, S.Q. (2007). Bioregenerative Engineering Principles and Applications. New Jersey: Wiley- Interscience.
• Laurencin, C.R., Nair, L.S., and Rao, C.N.R. (2008). Nanotechnology and Tissue Engineering: The Scaffold. London: CRC Press
• Malsh, N.H. (2005). Biomedical Nanotechnology. London: CRC Press

Credit Hours - 3

Objective

The objective of the course is to equip students with the knowledge sets for advanced concepts in polymer science as applied to biomaterials. The course continues to provide knowledge of major experimental concepts that reveal the material chemistry.

Content

Glassy, rubbery, and organized states of bulk polymers; solid-state structure; dynamics; and mechanical properties of non-crystalline and semi-crystalline polymers are all modern concepts. It considers polymer viscoelasticity, diffusion, failure mechanisms, and elementary polymer rheology. A review of the principal experimental methods and applications in biomaterials applications is also considered.

Reading list

• Piskin, E., Allan S. H., (2008). Polymeric Biomaterials. Springer Netherland.
• Griffith, L.G., 2000. Polymeric biomaterials. Acta materialia, 48(1), pp.263-277.
• Xia, D., Chen, J., Zhang, Z. and Dong, M., 2022. Emerging polymeric biomaterials and manufacturing techniques in regenerative medicine. Aggregate, p.e176.
• Ijaola, A.O., Akamo, D.O., Damiri, F., Akisin, C.J., Bamidele, E.A., Ajiboye, E.G., Berrada, M., Onyenokwe, V.O., Yang, S.Y. and Asmatulu, E., 2022. Polymeric biomaterials for wound healing applications: a comprehensive review. Journal of Biomaterials Science, Polymer Edition, pp.1-53.
• Helmus, M.N (2003), Biomaterials in the Design and Reliability of Medical Devices. New
• Jayakumar, R., Prabaharan, M., Riccardo A. & Muzzarelli, A.(2011). Chitosan for Biomaterials I (Advances in Polymer Science).
• Kutz, M. (2009). Biomedical Engineering and Design Handbook. New York: Wiley. 23, 23-35
• Leal-Egana, A.,Diaz-Cuenca, A., &Boccaccini, A. R., (2013). Tuning of cell-biomaterial anchorage for tissue regeneration. Advanced Materials.25, 4049-4057
• Lee, J. Y., Choi, B., Wu, B., &Lee, M., (2013). Customized biomimetic scaffolds. York: Wiley

Credit Hours - 3

Objective

The goal of this course is to use a problem-solving approach to teach students how to review and interpret literature to enable them construct, apply and justify biomechanical factors that are influenced by injury, loading and ageing.

Content

This course covers the principles of engineering mechanics in the examination of human physiological subsystems such as the musculoskeletal system and the cardiovascular system. Topics drawn for biosolid mechanics, biofluids, and biodynamics, the viscoelastic modeling of muscle and bone, non-Newtonian fluid rheology, blood flow dynamics, respiratory mechanics, biomechanics of normal and impaired gait, and sport biomechanics. Hard tissues: Bone structure & composition.

Reading list

• Alexander, R. M. (1975). Biomechanics. New York: Chapman and Hall.
• Chien, S.(2008).An introductory Text to Bioengineering(Advanced Series in Biomechanics)[Paperback]. New York: World Scientific Publishing Company 
• Fung. Y. C. (1997). Biomechanics -Circulation. New York: Springer Verlang.
• Ghista. D. N. & Dekker, M. (1982).   Biomechanics of Medical Devices.New York: Macel Dekker.
• Hall, S. J. (2003). Basic Biomechanics. New York: McGraw-Hill.
• Lee, C. H., Shih, k. S., Hsu, C. C., &Cho, T., (2013). Simulation-based particle swarm optimization and mechanics validation of screw position and number for the fixation stability of a femoral locking compression plate.  Medical Engineering Physics.doi:10.1016/j. medengphy.
• Wan, C.,Hao, Z. X.,&Wen, S. Z.,(2013). The effect of the material property change of anterior cruciate ligament by ageing on joint kinematics and biomechanics under tibialvarus/valgus torques. Biomedical Material Engineering.23, S1427-S1434.
   

Credit Hours - 3

Objective

This program aims to prepare students to comprehend contemporary high throughput technologies and their applicability to real biological and biomedical challenges, as well as to master systems biology theories and algorithms. The program also intends to provide students with expertise in building projects utilizing high-throughput data to discover physiologically meaningful characteristics using systems biology methodologies. It also seeks to equip students with a thorough understanding of network and route analysis utilizing 'omics' data.

Content

The course will include lectures, discussions, and practical computational exercises covering the following topics: genomics which encompasses Genome-scale mutational profiling in complex diseases, regulation in biological systems and high-performance genomic technologies, and data analysis which includes microarray and next generation sequences analysis. Systems genetics, molecular evolution, and phylogenetics elucidate the use of phylogenetics techniques to study the genetic diversity of viruses. GWAS Population genomics describes linkage disequilibrium; genome-wide association mapping, disease genomics, and adaptation genomics. Transcriptomics methods focus on microarrays, SAGE, tiling arrays, splicing assays, RNA-seq, Chip-Seq, sequencing vs. microarrays, clustering, other analysis techniques, and differential expression analysis. Also, it includes proteomics with focus on 2D gels, mass spectrometry, tagged proteins (libraries); interactions, biomarkers, and translation regulation. It also integrates metabolomics & metabolic networks which describes the integration of metabolomics and phenomics to understand genomic data. The module also includes Signal transduction networks which outlines dynamic systems modeling, signaling networks, dynamic signaling and gene expression, feedback loops, and synthetic biology. It also introduces Biomedical Imaging and informatics which equips students with mathematical algorithms used in the processing and analysis of biomedical images.

Reading list

• Biesbroek G., Tsivtsivadze E., Sanders E.A., Montijn R., Veenhoven R.H., Keijser B. J. (2014). Early respiratory microbiota composition determines bacterial succession patterns and respiratory health in children. Am J Respir Crit Care Med.; 190 (11: 83–92).
• Camelo-Castillo A, Henares D, Brotons P, Galiana A, Rodriguez JC, Mira A and Muñoz-Almagro C. (2019). Nasopharyngeal Microbiota in Children with Invasive Pneumococcal Disease:  Identification of Bacteria with Potential Disease-Promoting and Protective Effects. Frontiers Microbiology; 10:11. doi: 10.3389/fmicb.2019.00011
• Zvelebil, Marketa, and Jeremy O. Baum. Understanding Bioinformatics. New York, NY: Garland Science, 2007. ISBN: 9780815340249.
• Alon, Uri. An Introduction to Systems Biology: Design Principles of Biological Circuits. Boca Raton, FL: Chapman & Hall, 2006. ISBN: 9781584886426. 
• Watson, J. D., T. A. Baker, S. P. Bell, A. Gann, M. Levine, and R. Losick. Molecular Biology of the Gene. 6th ed. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 2007. ISBN: 9780805395921.
• Alberts, B., A. Johnson, J. Lewis, M. Raff, K. Roberts, and P. Walter. Molecular Biology of the Cell. (5th Ed). New York, NY: Garland Science, 2008. ISBN: 9780815341055.
• Berg, J. M., J. L. Tymoczko, and L. Stryer. Biochemistry. (6th Ed). New York, NY: W.H. Freeman, 2007. ISBN: 9780716787242.

Credit Hours - 3

Objective

This module is aimed at equipping students with knowledge on bioethics, biosafety, and clinical trials to help deal with controversial ethical issues emerging from new situations and possibilities brought about by advances in biology and medicine. It is also aimed at emphasizing the prevention of large-scale incidents and any harmful effects on people and environment due to biological research. It also aims to equip students on how to conduct clinical trials and the protocols they need to observe.

Content

This course examines biosafety concepts and processes including biohazards, classification of pathogens, biosafety cabinets, and decontamination as well as their relevance to biomedical engineers. Various disciplines, standards, degrees, and applications of biosafety ideas will also be explored. The ethical concerns that occur in biology and medicine particularly human participants in research are addressed in the second stage. This includes identifying the risks a research project might pose to participants, describing additional protections needed for vulnerable populations and outlining appropriate procedures for recruiting research participants and getting informed consent. The course will also emphasize how the process of modern research produces pressures that might lead to scientific deception. Ethical issues raised by current inventions will also be addressed. The module will also discuss the various stages or phases of clinical trials for drugs and medical devices. It will also elaborate on the classes of medical devices and the cost of medical device trials.

Reading list

• Kimman TG, Smit E, Klein MR. (2005). Evidence-based biosafety: a review of the principles and effectiveness of microbiological containment measures. Clin Microbiol. 21 (3):403-25. 
• Bioterrorism. Emerg Infect Dis. 11 (8):1180-5. 
• Bonis, M. D. &Costa, M. A.(2009). Education on biosafety and bioethics: necessary articulation in biotechnology. Cencia Saude Coletiva 6, 2107-2114.
• Goel, D. &Parashar, S. (2013). IPR, Biosafety and Bioethics. Pearson Education, India
• Garrett, J.R. (2012). The Ethics of Animal Research: Exploring the Controversy (Basic Bioethics). MIT Press; 1st Ed. (2012).

Credit Hours - 3

Objective

This module is aimed at equipping students to apply bioinformatics, genomics, and computational biology concepts to analyse biomedical data pertaining to infectious and tropical diseases. This module also aims to emphasize the application of principles, concepts, algorithms, and theories underlying bioinformatics to model biological systems, understand fundamental cellular processes, and identify specific biomarkers, drug, and vaccine targets.

Content

The module will include lectures, discussions, and practical computational exercises covering the following topics: Biocomputing which involves the use of programming languages and software such as R, Python, and MySQL to analyze biological data. It also encompasses exploratory data analysis, and essential statistics using R. It also emphasizes the exploration of DNA and protein databases and performing similarity searches using BLAST, NCBI, ENSEMBL tools as well as biomedical text mining. Also, graph theory algorithms and mathematical modeling will be explored for the discovery of hypothesis of therapeutic relevance. In addition, the module includes the construction and analysis of protein interaction networks which uses topological characteristics of biomolecular networks and pathway analysis to identify functional modules with implicated in disease mechanisms. Other major topics to be covered include the prioritization of candidate disease genes using genomic fusion and network analysis, the use of artificial intelligence algorithms, machine learning techniques, and features of genomics and proteomic data to identify novel biological inferences, OMICs, genomics, and regulation in biological systems using high-performance genomic technologies and data analysis.

Reading list

• Attwood, T.K. & Parry-Smith, D.J. (1999) Introduction to Bioinformatics. Pearson Education, UK. ISBN: 0582327881
• Gotoh O. (1999). Multiple Sequence Alignment: Algorithms and Applications. Advanced Biophysics,  36:156-206.
• Higgs, P. & Attwood, T.K. (2005). Bioinformatics & Molecular evolution. Blackwell: Oxford, UK.  ISBN: 1405106832
• Lesk, M. A. (2014). Introduction to Bioinformatics (4th ed). Oxford University Press: Oxford, UK.
• Byron, K., Herbert, K., & Wang, J. (2016). Bioinformatics database systems (1st ed.). CRC Press.
• Zvelebil, Marketa, and Jeremy O. Baum. Understanding Bioinformatics. New York, NY: Garland Science, 2007. ISBN: 9780815340249.

Credit Hours - 3

Objective

The objective of this course is to train students to acquire necessary skills on modern and professional methods and techniques of designing hospitals/ healthcare facilities with the aim of minimizing cost, providing safety for occupational workers, patients and caretakers; and facilitating rapid healing/recovery of patients.

Content

This course will cover topics such as, electrical power quality and reliable operation of high-tech medical equipment; electrical safety in the patient care environment; electromagnetic compatibility of various medical devices and electromagnetic interference; radiation shielding and radiation protection; medical gas systems, medical ventilation systems and indoor air quality; fire protection systems required in the hospital; networking medical devices, patient information management systems, digital imaging and image storage systems; telemedicine and medical linage transmission; and finally, hospital architecture and the design of patient care facilities.

Reading list

• Bonnema, E., Pless, S. & Doebber, I. (2010). Advanced Energy Design Guide for Small Hospitals and Healthcare Facilities. Multi-Science Publishing ISSN 1756-8250
• ASHRAE. (2012). Advanced Energy Design Guide for Large Hospitals. ASHRAE: ISBN-13: 978-1936504237 
• Grunden, N.&Hagood, C. (2012). Lean-Led Hospital Design: Creating the Efficient Hospital of the Future. New York: Productivity Press.
• Gupta, K. (2007). Modern Trends in Planning and Designing of Hospitals: Principles and Practice. New Delhi: Jaypee Brothers Medical Publishers.
• Kunders, G.D. (2004). Hospitals: Facilities. Planning and Management. Tata McGraw-Hill Publishing House: ISBN: 0070502692, 9780070502697

Credit Hours - 3

Objective

One objective of this course is to provide students with the opportunity to explore topics in their fields of studies to gain in depth knowledge in these fields and to survey and critically evaluate different viewpoints of academicians. Another objective of the course is to facilitate bridging the gap in communication between students and their lecturers; and to help students gain the necessary confidence needed for presentations at national or international seminars and conferences.

Content

During the seminar session each student is expected to prepare a talk on a selected topic in biomedical engineering and give a presentation. The topic will be the basis for the student research work. A faculty guide is to be allotted and he / she will guide and monitor how the students handle questions pertaining to the topic. Students are encouraged to use various teaching aids such as overhead projectors, power point presentation and demonstrative models.

Reading list

• Chambers, H.E. (2000). Effective Communication Skills for Scientific and Technical Professionals Paperback. New York: Basic Books.
• Cohen, W.A. (2001). How to Make It Big as a Consultant. London: AMACOM 
• Jolles, R. L. (2005). How to Run Seminars & Workshops: Presentation Skills for Consultants, Trainers and Teachers Paperback. New Jersey: Wiley.
• Kahrs. T.K. (2009). Presentation Skills Mastery. CreateSpace.
• Maselli, F. (2002). Seminars: The Emotional Dynamic Advanced Presentation Skills for Financial Professionals. London: Creative Image. 
• Robson, C. (2002). Real World Research: A Resource for Social Scientists and Practitioners 
• Sony. Seminar Series - Professional Training for Vegas 6 Software.
• Sony Media Soft STV2000.

Credit Hours - 3

Objective

The objective of this course is make students gain in-depth knowledge of biological systems and to train them on the basic principles of bioinstrumentation and electric circuit design for bioinstrumentation so that they gain essential skills that will enable them apply science and engineering techniques to design instrumentation for biomedical applications.

Content

Topics covered under this course include, origins of bioelectric signals analysis and design of electrodes and low noise preamplifiers used in their measurement, the electric circuit theory, statistical techniques applied to the detection and processing of biological signals, denoising, signal conditioning, useful information extraction and display. Also, methods of identifying the dynamic properties of biosystems will be taught.

Reading list

• Bialek, W. (2012). Biophysics: Searching for Principles. New Jersey: Princeton University Press.
• Dimitrov, G.V., Dimitrova, N. A .Pajeva, I. K. (1992). Threshold stimulation and accommodation of the Hodgkin-Huxley, axon. General Physiology Biophysics.11, 59-68. 
• Enderle, J.D. (2006). Bioinstrumentation (Synthesis Lectures on Biomedical Engineering Synthesis Lecture). Morgan and Claypool Publishers, California.
• Liu J, Hogan NC, Hunter 1W. (2012). Intradermal needle-free powdered drug injection by a helium-powered device. IEEE Engineering Medical Biology Society.2012, 2068-2071. 
• Ronald R. Pethig, R.R.&Smith, S. (2012). Introductory Bioelectronics For Engineers and Physical Scientists. New Jersey: Wiley. 
• Webster, J.G. (2003). Bioinstrumentation. New Jersey: Wiley.
• Webster, J.G. (1994). Medical Instrumentation. New Jersey: Wiley.

Credit Hours - 3

Objective

This module is aimed at equipping students with the knowledge and skills necessary to apply mathematical algorithms, modeling, and simulation principles to computational bioengineering research challenges. The module also aims to emphasize the application of concepts and algorithms computational bioengineering to model biological systems, comprehend fundamental cellular processes, and identify specific biomarkers, drug, and vaccine targets.

Content

The course will include lectures, discussions, and practical computational exercises covering the following topics: introduction to computational bioengineering and its applications in addressing local biomedical healthcare needs, application of computational bioengineering in integrative physiological modeling, drug design, bioinformatics, and systems biology. The course also encompasses multi-scale modeling and system biology by integrating genomics, proteomics, and tissue electro-mechanics, modeling and computation for functional genomics, machine learning algorithms, computational modeling, and molecular dynamics (MD) simulation. It also address mathematical algorithms used in the processing and analysis of biomedical images (Biomedical imaging and informatics). Finally, the course elucidates computational bioengineering for vaccines, and using computational bioengineering to identify biomarkers using omics data.

Reading list

• Martin J., (2013). Python for Biologists. CreateSpace Independent Publishing Platform: California, USA. ISBN: 1492346136.
• Barrett, J. D. (2018). Linux Pocket Guide (2nd ed). O’Reilly Media, Inc: California, USA. ISBN: 1449316697
• Sebastian B. (2010). Python for Bioinformatics. Taylor and Francis Group, LLC: Florida, USA
• Wickham, H., & Grolemund, G., (2016). R for Data Science. O’Reilly Media, Inc: California, USA
• Crawley, M. J., (2013). The R Book (2nd ed). Wiley and Sons Publications: USA
• Zhang G. (2015). Introduction to Computational Bioengineering: A Multidisciplinary Approach. CRC Press. ISBN 1466572280, 9781466572287.
• Zvelebil, Marketa, and Jeremy O. Baum. Understanding Bioinformatics. New York, NY: Garland Science, 2007. ISBN: 9780815340249.

Credit Hours - 3

Objective

The objective of this course is to equip students with the knowledge sets in medical diagnosis and treatment required in the design of medical instrumentation systems.

Content

Technologies to be covered will be selected from anesthesia equipment, surgical and ophthalmic lasers, cardiac assisted devices, surgical and endoscopic video systems, radiographic and fluoroscopic devices, CT, MRI, ultrasound imaging equipment, radiation therapy, nuclear medicine, clinical chemistry analyzers, spectrophotometers, and hematology analyzers.

Reading list

• Murugan, R.K.V. (2021). Diagnostic and therapeutic equipment - 1. Notion Press.
• Alaei, P. (2008). Introduction to health physics. (4th Ed.). American Association of Physicists in Medicine.
• Avansino, J. R., Goldin. A.B., Risley, R., Waldhausen, J.H. & Sawin, R. S. (2013). Standardization of operative equipment reduces cost. Journal Pediatrics. Surgery.48. 1843-1849.
• Jin, Z. D.&Guo, J. F. (2013). Application of endoscopic ultrasonography in the diagnosis and management of gastrointestinal cancers. Zhonghzia Wei Chang WaiKeZaZhi., 16, 411-414. 
• Northrop, R. B. (2002). Noninvasive Instrumentation and Measurement in Medical Diagnosis. London: CRC Press.
• Tobler, W. D.,Melgar, M. A.,Raley, T.J., Anand, N., Miller, L.E. & Nasca, R. J. (2013). Clinical and radiographic outcomes with L4-S1 axial lumbar interbody fusion (AxiaLIF) and posterior instrumentation: a multicenter study. Medical Devices.18,155-161.

Credit Hours - 3

Objective

The experiential research learning (ERL) seminar will prepare the student to stag an apprenticeship soon after their comprehensive examination. Students shall be required to undergo practical training with Faculty in research work and present a report on their experience at the end of the second year. The student is also expected to report on the students' work. Other areas the student can work is in industries, hospitals and institutions.

Reading list

• Chambers, FI.E. (2000). Effective Communication Skills for Scientific and Technical Professionals Paperback. New York: Basic Books.
• Cohen, W.A. (2001). How to Make It Big as a Consultant. London: AMACOM 
• Jolles, R. L. (2005). How to Run Seminars. & Workshops: Presentation Skills for Consultants. Trainers and Teachers Paperback. New Jersey: Wiley.
• Kahrs. T.K. (2009). Presentation Skills Mastery. CreateSpace.
• Maselli, F. (2002). Seminars: The Emotional Dynamic Advanced Presentation Skills fin. Financial Professionals. Creative Image, London. 
• Sony, (2000). Seminar Series - Professional Training for Vegas 6 Software. Sony Media Sof1STV2000.

Credit Hours - 3

Objective

This seminar is intended to provide an opportunity for the candidate to present the progress report on the research. This is an opportunity for the candidate to solicit advice and ideas to move forward. A faculty guide is to be allotted and he/she will guide and monitor the progress of the student and maintain attendance. Students are encouraged to use various teaching aids such as overhead projectors, power point presentation and demonstrative models. This will enable them to gain confidence in facing placement interviews.

Reading list

• Chambers, FI.E. (2000). Effective Communication Skills for Scientific and Technical Professionals Paperback. New York: Basic Books.
• Cohen, W.A. (2001). How to Make It Big as a Consultant. London: AMACOM 
• Jolles, R. L. (2005). How to Run Seminars. & Workshops: Presentation Skills for Consultants. Trainers and Teachers Paperback. New Jersey: Wiley.
• Kahrs. T.K. (2009). Presentation Skills Mastery. CreateSpace.
• Maselli, F. (2002). Seminars: The Emotional Dynamic Advanced Presentation Skills fin. Financial Professionals. Creative Image, London. 
• Sony, (2000). Seminar Series - Professional Training for Vegas 6 Software. Sony Media Sof1STV2000.

Credit Hours - 3

Objective

The candidate will give his presentation on the preliminary findings and highlight what is yet to be done. This is an opportunity for the candidate to put the final thesis together. A faculty guide is to be allotted and he / she will guide and monitor the progress of the student and maintain attendance. Students are encouraged to use various teaching aids such as overhead projectors, power point presentation and demonstrative models. This will enable them to gain confidence in facing placement interviews.

Reading list

• Chambers, FI.E. (2000). Effective Communication Skills for Scientific and Technical Professionals Paperback. New York: Basic Books.
• Cohen, W.A. (2001). How to Make It Big as a Consultant. London: AMACOM 
• Jolles, R. L. (2005). How to Run Seminars. & Workshops: Presentation Skills for Consultants. Trainers and Teachers Paperback. New Jersey: Wiley.
• Kahrs. T.K. (2009). Presentation Skills Mastery. CreateSpace.
• Maselli, F. (2002). Seminars: The Emotional Dynamic Advanced Presentation Skills fin. Financial Professionals. Creative Image, London. 
• Sony, (2000). Seminar Series - Professional Training for Vegas 6 Software. Sony Media Sof1STV2000.

Credit Hours - 3

Objective

The objective of this course is to train students the principles and developmental processes involved in conducting effective research and how to write scientific reports on research.

Content

Topics include research process, development of research proposals, design of questionnaire and interviewing techniques, content analysis, research report writing, quantitative and qualitative research, measurement strategies, sources of data and collection procedures, literature survey, statistical evaluation of data and testing, experimental research design, factorial experiment, nested design, split-plot design, statistical software packages.

Reading List

• Wyman, A. (2001). Social Research Methods (1st ed.). Oxford University Press.
• Campbell, D. T., & Stanley, J. C. (1990). Experimental and Quasi-Experimental Designs for Research. Houghton Mifflin Publishers. International Journal of Qualitative Research Methods. International Journal of Social Research Methodology. Journal of Research Practice.
• Madsen, D. (1991). Successful Dissertation and Theses: A Guide to Graduate Student Research from Proposal to Completion. New Jersey: Jossey-Bass Inc. Publishers.
• Robson, C. (2002). Real-World Research: A Resource for Social Scientist and Practitioners. New Jersey: Blackwell Publishers.

Credit Hours - 3

Objective

The objective of this course is to train students on the theoretical, practical and strategic development management tools necessary to manage a project.

Content

Topics include scope and value of the project, project clarity and goals, systems engineering, management processes and strategies, various functional areas in project management including project planning, organizing, monitoring and control, integration, communication and reporting, risk management, human resource management, procurement management, engineering economics including for-profit and not-for-profit decision-making, uncertainty, and multiple attribute decisions.

Reading List

• Kerzner, H. (2013). Project Management: A Systems Approach to Planning, Scheduling, and Controlling. New Jersey: John Wiley.
• Lock, D. (2007). Project Management. Hampshire: Gower Publishing.
• Meredith, J. R., & Mantel, S. J. (2012). Project Management: A Managerial Approach. New Jersey: John Wiley. Project Management Journal.
• Ross, S. M. (2006). Project Management, Planning and Control: Managing Engineering, Constructions and Manufacturing Projects. London: Butterworth Heinemann.

Credit Hours - 3

Objective

The objective of this course is to provide students with an opportunity to design high-performance and scalable algorithms for computational bioscience & engineering applications.

Content

The course focuses on algorithm design, complexity analysis, experimentation, and optimization, for important biomedical science and engineering applications. Students will develop knowledge and skills concerning: the design and analysis of real-world algorithms employed in computational bioscience and engineering applications, and performance optimization of applications using the best practices of algorithm engineering.

Reading List

• Boyd, D. W. (2000). System Analysis and Modeling: Macro-to-Micro Approach with Multidisciplinary Applications. Harcourt: Academic Press.
• Chandra, R. (2001). Parallel Programming in OpenMP. Academic Press.
• Cristianini, N., Shawe-Taylor, J., & Holloway, R. (2000). An Introduction to Support Vector Machines and Other Kernel-based Learning Methods. London: CRC Press.
• Deo, N. (1983). System Simulation with Digital Computer. India: Prentice Hall.
• Grama, A., Karypis, G., Kumar, V., & Gupta, A. (2003). Introduction to Parallel Computing. Boston: Addison Wesley.
• IEEE Transactions on Parallel and Distributed Computing.
• Panchenko, A., & Przytycka, T. M. (2008). Protein-protein Interactions and Networks Protein, Identification, Computer Analysis, and Prediction Series. London: CRC Press.

Credit Hours - 3

Objective

The objective of this course is to train PhD students, starting with how to choose a research top area, framing of a research question, the use of the right tools and techniques to gather data, the use of the right methods to analyse research data, reporting of research results and the ethics involved in doing research.

Content

The topics to be covered include research definition, objectives of research, importance of research, types of research, motivation for research, approaches to research, research processes/procedures, statistical concepts used in research, parametric data analysis methods, non-parametric data analysis methods, application of statistical data analysis tools for data analyses, drawing of inferences, report writing and research ethics.

Reading list

•  Bantley, J. P. (2002). Principles of measurement systems. 2nd Edition. New York, NY: Longman Scientific and Technical
• Campbell, D. T., & Stanley, J. C. (1990). Experimental and quasi-experimental designs for research. Boston, MA: Houghton Mifflin Publishers
• Holman, J. P. (1994). Experimental methods for engineers. New York, NY: McGraw-Hill Inc 
• Houp, K. W., &Pearsall, T.E.(1992). Reporting technical information. New York, NY: Macmillan Publishing Co.
• Lipson, C., & Sheth, N.J. (1983). Statistical design and analysis for engineering experiments. New York, NY: McGraw-Hill Book Co.
• Myers  R.H., & Montgomery, D.C (2002). Response surface methodology: Process and product optimization using design experiments. New York, NY: John Wiley & Sons Inc
• Snijders, T. A. B., & Bosker, R. (2011). Multilevel Analysis: An introduction to a Basic and Advanced Multilevel Modeling. 2nd Edition, California: SAGE Publication Ltd.
   

Credit Hours - 3

Objective

The of objective of this course is to train students to gain the knowledge and skills needed to assess a project, draw a project plan, manage stakeholders, organize a team and train the team to understand the scope, requirements and purpose of the project and to persuade or motivate the team perform the various parts/aspects of the project with the ultimate aim of finishing the project within stipulated time at a minimum cost.

Content

Topics to be taught include, avoiding mistakes when executing and controlling a project, dealing with evolving stakeholder expectations, using trend analysis to measure project, project selection and initiation, project execution and methodology, project variance and control as well as project closure and learning. Advanced and newly developed quality control and improvement methods such as modified and acceptance charts, multiple stream process control, control charts with adaptive sampling and engineering process control for quality, international standards of acceptance sampling, economic design and implications of quality control and improvement procedures will also be taught.

Reading list

• Fox, W. & Waldt, G. V. D. (2008). A Guide to Project Management. Claremont: Juta and Company Ltd
• Kerzner, H. R. (2010). Project Management – Best Practices: Achieving Global Excellence. 2nd Edition. New Jersey: Wiley
• Kerzner, H. R. (2013). Project Management Metrics, KPIs, and Dashboards: A Guide to Measuring and Monitoring Project Performance. 2nd Edition. New Jersey: Wiley
• Kerzner, H. R. ( 2005). Using the Project Management Maturity Model: Strategic planning for Project Management. 2nd Edition. New Jersey: Wiley
• Lewis, J. (2007). Mastering Project Management: Applying Advanced Concepts to Systems Thinking, Control and Evaluation, Resource Allocation.  2nd Edition. New York: Mc Grawhill.
• Lock, D. (2007) Project Management. Burlington: Gower Publishing Ltd
• Meredith, J. R., and Mantel, S. J., (2012). Project Management: A Managerial Approach, New Jersey: Wiley