The course covers various aspects of optimization theory with applications to large-scale energy networks such as the electrical power grid, gas and oil field networks. Several control paradigms and optimization techniques that enable our modern way of living will be presented.This course covers the following topics: engineering systems modeling for design and optimization, selection of design variables, objective functions and constraints, overview of principles, methods and tools in multidisciplinary design optimization for systems, subsystem identification, development and interface design, review of linear and non-linear constrained optimization formulations.