h22Mahmood Brobbey Oppong

Address:          Room 18, School of Pharmacy, University of Ghana Legon

Tel:                  02086360510, 0543197876     

Email:              mboppong@ug.edu.gh ; mahmood.obrobbey@gmail.com 

ORCID:           https://orcid.org/0000-0002-0439-6466; 

Scopus ID:      https://www.scopus.com/authid/detail.uri?authorId=57191187927 

PubMed:          https://pubmed.ncbi.nlm.nih.gov/?term=mahmood+brobbey+oppong 

Research Gate: https://www.researchgate.net/profile/Mahmood-Oppong 

Google Scholar: https://scholar.google.com/citations?hl=en&user=9GAgfL4AAAAJ 

Current Research

  1. Quality assessment and misuse/abuse of medicines (orthodox and herbal)

Development of analytical methods for the qualitative and quantitative assay of pharmaceuticals (orthodox and herbal medicines) and pharmaceutical contaminants in food.

  1. Detection of levels of paracetamol and para-aminophenol in foods.
  2. Quantitative estimation of aflatoxins in herbal products using high performance liquid chromatography.

     1. Natural product research

Focusing specifically on innovative research to scientifically validate folkloric use of indigenous traditional medicines that will ultimately lead to the discovery of potential lead compounds.

  1. Isolation, identification and characterization of medicinal plant isolates using chromatographic and spectroscopic methods.
  2. In vitro and in vivo activity screening 
  3. Profiling of bioactive constituents of local medicinal plants.

Education

2015 – 2018    Doctor of Philosophy (PhD), School of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin, China.

2011 – 2014    Master of Philosophy (MPhil), Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

2006 – 2010    Bachelor of Pharmacy (B. Pharm), Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.

Teaching and Research Experience

2021                Senior Lecturer, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Ghana, Accra

2019 - 2021     Lecturer, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Ghana, Accra

2015 – 2018    Assistant Lecturer, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Ghana, Accra

2012 – 2013    Graduate Assistant, Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

2010 – 2012    Teaching Assistant, Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Pharmaceutical Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana

Administrative Experience

Aug. 2024 -                             Head, Department of Pharmaceutical Chemistry

Sept. 2022 – Aug. 2024          Examination Officer, School of Pharmacy, University of Ghana

Mar. 2022 -                             Hall Tutor, Legon Hall, University of Ghana

Oct. 2020 –                             E-learning Ambassador, Department of Pharmaceutical                                         Chemistry, School of Pharmacy, University of Ghana

May 2020 –                             Quality Control Officer, School of Pharmacy, University of                                   Ghana

Jan. 2020 – Aug 2024             Laboratory Coordinator, Department of Pharmaceutical                                       Chemistry, School of Pharmacy, University of Ghana

Publications

  1. Niu, Z., Chen, C. Y., Zhou, Y., Liu, G. K., Zhang, B. Y., Oppong, M. B., Zhang, D. Q., Yao, T., & Qiu, F. (2024). Characterization of Sesquiterpene Dimers from the Flowers of Inula japonica and the Structural Revisions of Related Compounds. Journal of Natural Products,87(7), 1754-1762. https://doi.org/10.1021/acs.jnatprod.4c00269
  2. Mahmood B. Oppong, Shijie Cao, Shi-Ming Fang, Seth K. Amponsah, Paul O. Donkor, Michael Lartey, Lawrence A. Adutwum, Kwabena F.M. Opuni, Feng Zhao, Qiu Feng (2024) In-vitro and in-vivo anti-inflammatory properties of extracts and isolates of Pangdahai. Phytomedicine plus. Volume 4, Issue 2, 100533, https://doi.org/10.1016/j.phyplu.2024.100533
  3. Ewurabena Y. Afful, Samuel Frimpong-Manso, Samuel O. Bekoe, Chris O. Barfi, Kwabena F.M. Opuni, Mahmood B. Oppong (2022). The Unethical Use of Paracetamol As a Food Tenderizer in Four Selected African Countries: A Major Public Health Concern? Drug Metabolism and Bioanalysis Letters. http://doi.org/10.2174/2949681015666220810125820 
  4. Yang, Miaojie; Oppong, Mahmood Brobbey; Di, Jingrui; Yuan, Qing; Chang, Yanxu; Jiang, Miaomiao; Cao, Shijie; Dong, Pengzhi; Li, Lin; Xie, Yan; Luan, Xiaoying; Hu, Limin; Chai, Lijuan; Zhang, Peng (2022). Steroidal saponins with anti-inflammatory activity from Tribulus terrestris L. Acupuncture and Herbal Medicine: Volume 2, Issue 1, p 41-48. http://doi.org/10.1097/HM9.0000000000000026
  5. Boateng A. A., Sumaila S., Lartey M., Oppong M. B., Opuni K. F. M., Adutwum L. A. (2022). Evaluation of chemometric classification and regression models for the detection of syrup adulteration in honey, LWT, 2022. http://doi.org/10.1016/j.lwt.2022.113498
  6. Mahmood Brobbey Oppong, Bing-Yang Zhang, Shi-Ming Fang, Feng Qiu (2020). Secondary metabolites from Sterculia lychnophora Hance (Pangdahai). Biochemical and Systemic Ecology, 92, 104125, 1-4
  7. Yan-Li Huang, Mahmood Brobbey Oppong, Ying Guo, Li Zhi Wang, Shi-Ming Fang, Yan-Ru Deng, Xu-Mei Gao (2019). The Oleaceae family: A source of secoiridoids with multiple biological activities. Fitoterapia. http://doi.org/ 10.1016/j.fitote.2019.04.010 
  8. Mahmood Brobbey Oppong, Li Yang, Prince Osei Banahene, Fang Shi-Ming, Qiu Feng (2018). Ethnopharmacology, phytochemistry and pharmacology of Sterculia lychnophora Hance (Pangdahai) Chinese Journal of Natural Medicines. 16(10): 721-731 http://doi.org/10.1016/S1875-5364(18)30112-2s. 
  9. Xinchi Feng, Yang Li, Mahmood Brobbey Oppong, Feng Qiu (2018). Insights into the intestinal bacterial metabolism of flavonoids and the bioactivities of their microbe-derived ring cleavage metabolites. Drug Metabolism Reviews, 1-14
  10. Cheng-Peng Sun, Mahmood Brobbey Oppong, Feng Zhao, Li-Xia Chen and Feng Qiu (2017). Unprecedented 22,26-seco physalins from Physalis angulata and their anti-inflammatory potential. Organic and biomolecular chemistry, 15(41), 8700–8704. http://doi.org/10.1039/c7ob02205k
  11. Li-Qin Ding, Tian-Yi Qiu, Zhao-Xi Liu, Li-Xia Chen, Mahmood Brobbey Oppong, De-Qin Zhang, Bo-li Zhang, Gang Bai, Feng Qiu (2017). Systematic characterization of the metabolites of paeonol in rats using ultra performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight tandem mass spectrometry with an integrative strategy. Journal of Chromatography B 1065–1066 (2017) 70–78.
  12. Yaqing Guoa, Hongxia Liu, Liqin Ding, Mahmood B. Oppong, Guixiang Pan, Feng Qiu (2017). LC-MS/MS method for simultaneous determination of flavonoids and physalins in rat plasma: application to pharmacokinetic study after oral administration of Physalis alkekengi var. franchetii (Chinese lantern) extract. Biomedical chromatography doi: 10.1002/bmc.3970 31(10), e3970. 
  13. Liwei Chai, Paul Owusu Donkor, Kun Wang, Yingjie Sun, Mahmood Brobbey Oppong, Kai Wang, Liqin Ding & Feng Qiu (2017). Metabolic profiles of corydaline in rats by ultraperformance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry, Xenobiotica, 49(1):80-89, http://doi.org/10.1080/00498254.2017.1416207.
  14. John Teye Azietakua, Huifen Maa, Xie-an Yua, Jin Lia, Mahmood Brobbey Oppong, Jun Cao, Mingrui An, Yan-xu Chang (2017). A review of the ethnopharmacology, phytochemistry and pharmacology of Notopterygium incisum, Journal of Ethnopharmacology 202 (2017) 241–255, http://doi.org/ 10.1016/j.jep.2017.03.022
  15. Nan Zhang, Wei-xing Huang, Gui-yang Xia, Mahmood Brobbey Oppong, Li-qing Ding, Pan Li, Feng Qiu (2017). Methods for determination of absolute configuration of monosaccharides. Chinese Herbal Medicines 10 (1), 14–22, http://doi.org/10.1016/j.chmed.2017.12.009 
  16. Jin-Long Yao, Shi-Ming Fang, Rui Liu, Mahmood Brobbey Oppong, Er-Wei Liu, Guan-Wei Fan and Han Zhang (2016). A Review on the Terpenes from Genus Vitex. Molecules, 21(9), 1179. http://doi:10.3390/molecules21091179
  17. Mahmood B. Oppong, Samuel O. Bekoe, Reimel K. Adosraku, John S.K. Ayim (2015). Simultaneous quantification of five penicillins and detection of penicilloic acid in single and/or multi-component flucloxacillin pharmaceutical formulations. West African Journal of Pharmacy, 26 (1) 41-53.

Book chapter

  1. Newman Osafo, David Darko Obiri, Kwabena Owusu Danquah, Oduro Kofi Yeboah, Aaron Opoku Antwi, Mahmood Brobbey Oppong. Oxidative Stress and Neurodegeneration. In Handbook of Research on Critical Examinations of Neurodegenerative Disorders, Part of the Advances in Medical Diagnosis, Treatment, and Care Book Series. Chapter 2, page 24-47, http://doi: 10.4018/978-1-5225-5282-6.ch002

Board/Committee Membership

  1. Member, Board of Directors, Legon Club, University of Ghana
  2. Executive Member, University of Ghana School of Pharmacy Welfare, December 2022 to date
  3. Chairman, Supervisory Committee, Ghana Pharmacist Cooperative Credit Union Limited (GCPCUL)
  4. Member, Department Teaching Assessment Committee (DTAC), Department of Pharmaceutical Chemistry, School of Pharmacy.
  5. Member, Research and Grant Committee, Department of Pharmaceutical Chemistry, June 2019 – to date.
  6. Member, Faculty Board, University of Ghana School of Pharmacy, University of Ghana, Legon. 2019 to date
  7. Member, Academic Board, College of Health Sciences, University of Ghana, Legon, August 2024 to date
  8. Member, Academic Board, University of Ghana, Legon, August 2022 to date.
  9. Member, White Coat Ceremony Committee, School of Pharmacy, May 2022 to date
  10. Chairman, Risk and Safety Committee, School of Pharmacy, University of Ghana June 2021 to date.
  11. Chairman, Committee to deliberate and recommend project/programmes and activities to enhance socialization and closer fellowship among fellows of the Legon hall. September 2020 to date.

Professional Membership

i.         Member, Pharmaceutical Society of Ghana (PSGH), January 2012 to date.

ii.        Member, Universities Teachers Association of Ghana (UTAG), January 2015 to date

iii.       Member, Academic, Social and Research Pharmacists’ Association (ASRPA), May 2012 to date.

Advocacy

  1. Health Educationist, Phoenix Health Insurance, January 2020 till date
  2. Invited Speaker Radio Discussion on Use of Hydroxychloroquine in the treatment of COVID-19 hosted by Starr Fm. I gave education on the subject, explained the use of hydroxychloroquine and its role in treating COVID -19. 2nd April, 2020.  Starr FM studio, Accra. 
  3. Invited Speaker, Radio Discussion on Development of vaccines hosted by Starr Fm. I spoke and gave education on what is a vaccine, how vaccines are developed, clinical trials involved and how long it takes to get to the market. 4th March, 2020. Starr FM studio, Accra. 
  4. Thematic Speaker, 8th Annual General Conference of the Pharmacy Technologist Association of Ghana. Theme: Government of Ghana’s vision in making Ghana the Pharmaceutical hub of Africa, the role of the Pharmacy Technologist. 30th October - 2nd November 2019. Christ the King Parish, Accra, Ghana
  5. Facilitator, International Training on Qualification and Validation for Analytical Test Laboratories organized by Action Medeor (German Medical Aid Organization) and Kwame Nkrumah University of Science and Technology. March 13 – 15, 2013. KNUST, Kumasi.

Conferences

  1. College of Health Science 4th Biennial Scientific Conference, 28th – 30th September, 2022. La Palm Royal Beach Hotel, Accra, Ghana
  2. Restoring Hope Science Conference 2019. 30th October – 1st November, 2019 at Noguchi Memorial Institute for Medical Research. University of Ghana, Legon.
  3. International Conference on Quality Control of Traditional Chinese Medicines (TCM). 20th – 22nd August, 2017 at Tianjin State Key Laboratory of Modern Chinese Medicine of Tianjin University of TCM, Tianjin, China
  4. International Conference on Quality Control of Traditional Chinese Medicines (TCM). 12th – 14th August, 2016 at Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin, China
  5. International Conference on Harmonization of Traditional Chinese Medicines (TCM). 15th – 17th September 2015 at Tianjin International Joint Academy of Biotechnology and Medicine, Tianjin, China.
  6. Oppong, M.B., Ayim, JSK, Bekoe, SO 2014. A simple RP-HPLC method for the simultaneous quantification of five penicillins in either single or multi-component capsule dosage forms. 7th Annual GRASAG KNUST Research Conference. Kumasi.