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Margaret M. Lartey (MB.ChB. (Ghana), MSc (Wales), FWACP)

Margaret M. Lartey (MB.ChB. (Ghana), MSc (Wales), FWACP)
Associate Professor
mlartey@ug.edu.gh, larteym@chs.edu.gh, mlartey@chs.ug.edu.gh

Current Research Work

University of Ghana/Brown University Academic Partnership to Address HIV/AIDS in Ghana. The goal of this grant is to build capacity of the University of Ghana to conduct research, train and provide community service that contributes to enhanced response to the challenges of HIV/AIDS in Ghana.

 

 Original Publications in Peer-reviewed Journals

  1.  Kwamena William Coleman Sagoe, Afrakoma Adjoa Agyei, Francesca Ziga, Margaret Lartey, Theophilus K. Adiku, Makafui Seshi, Max Q. Arens, and Julius Abraham Addo Mingle. Prevalence and Impact of Hepatitis B and C Virus Co-Infections in Antiretroviral Treatment Naive Patients With HIV Infection at a Major Treatment Center in Ghana. Journal of Medical Virology 2012: 84:6–1.
  2. Awewura Kwara, Margaret Lartey, Kwamena W.Sagoe and Michael H. Court. Paradoxically elevated efavirenz concentrations in HIV/tuberculosis-coinfected patients with CYP2B6 516TT genotype on rifampin-containing antituberculous therapy. AIDS 2011: 25 (3); 388-39
  3. Lorna Renner, Musie Ghebremichael, Bamenla Goka, Margaret Lartey, Awewura Kwara and  Elijah Paintsil. Predictors of Trends were similar for absolute and percentage CD4+ T-Lymphocytes in HIV Infected Children in Ghana. Journal of Paediatric Infectious Diseases 2011:(6) 7-15
  4. Margaret Lartey, Kwamena W. Sagoe, Hongmei Yang, Ernest Kenu, Fafa Xexemeku, Joseph Oliver-Commey, Vincent Boima, Markafui Seshie, Augustine Sagoe, Julius A.A. Mingle, Timothy P. Flanigan, Hulin Wu, and Awewura Kwara. Viral Decay Rates are Similar in HIV-infected Patients with and without TB Coinfection during Treatment with an Efavirenz-based Regimen. Clinical Infectious Diseases 2011;52 (4):547–550
  5. I. W. Howley, M. Lartey, J. T. Machan, E. A. Talbot, A. Obo-Akwa, T. P. Flanigan and A. Kwara. Highly Active Antiretroviral Therapy and Employment Status in Accra, Ghana. Ghana Med J 2010: 44(4): 144-149
  6. Ayeh-Kumi P. F, Opoku A.G, Kwakye-Nuako G, Dayie N.T.K.D, Asmah RH, Obeng Nkrumah N, Lartey M, Sagoe A, Attipoe MI, Osafo KA, Kretchy JP, Sero-prevalence of toxoplasmosis among patients visiting the Korle-Bu Teaching Hospital, Accra, Ghana. RIF 1(3):147-150 (2010)
  7. Kwamin F, Hewlett S, Ndanu T.A, Lartey M, Nartey N.A. Incidence of Orofacial lesions in relation to CD4 Count in HIV/AIDS patients at the Fevers Unit-Korle-Bu Teaching Hospital. Ghana Dental Journal 2010: 7(1); 22-26
  8. Awewura Kwara, Margaret Lartey, Kwamena W.C. Sagoe, Ernest Kenu and Michael H. Court.  CYP2B6, CYP2A6 and UGT2B7 genetic polymorphisms are predictors of efavirenz mid-dose concentration in HIV-infected patients. AIDS 2009:23; 2101-2106
  9. Awewura Kwara,  Margaret Lartey,  Isaac Boamah, ,Naser L. Rezk,  Joseph   Oliver-Commey,  Ernest Kenu, ,Angela D. M. Kashuba,  Michael H. Court.  Interindividual Variability in Pharmacokinetics of Generic Nucleoside Reverse Transcriptase Inhibitors in TB/HIV-Coinfected Ghanaian Patients: UGT2B7*1c Is Associated With Faster Zidovudine Clearance and Glucuronidation. J. Clin. Pharmacol. 2009; 49; 1079-1090
  10. Topey K, Lartey M, Amenyah R, Addo NA, Obeng-Baah A, Rahman Y et al.  Initiating antiretroviral therapy in a resource-constrained setting: does clinical staging effectively identify patients in need?  International Journal of STD & AIDS 2009; 20: 395–398
  11. Awewura Kwara, Margaret Lartey, Kwamena W Sagoe, Naser L Rzek, Michael  H Court. CYP2B6 (c.516G>T) and CYP2A6 (*9B and/or *17) Polymorphisms are Independent Predictors of Efavirenz Plasma Concentrations in HIV-infected Patients.Br J Clin Pharmacol 2009; 67:4,427-436
  12. Kwara A, Lartey M, Sagoe KWC, Xexemeku F, Kenu E, Oliver-Commey J, Boima V,      Sagoe A, Boamah I, Greenblatt DJ, Court MH.  Pharmacokinetics of Efavirenz When Co-Administered With Rifampin in TB/HIV Co-Infected Patients: Pharmacogenetic Effect of CYP2B6 Variation. J Clin Pharmacol 2008;48:1032-1040
  13. Delgado Elena, Ampofo W K, Sierra Maria, Torpey K, Perez-Avarez Lucia, Bonney E Y, Mukadi Y D, Lartey M, Nyarko C et al.  High Prevalence of Unique Recombinant Forms of HIV-1 in Ghana: Molecular Biology from an Antiretroviral Resistance Study.  J Acquir Immune Defic Syndr 2008; 48(5): 599-606
  14. Sagoe KWC, Dwidar M, Lartey M et al.  Variability of the human immunodeficiency virus type 1 polymerase gene from treatment naïve patients in Accra, Ghana. J Clin Virol (2007), doi:10.1016/j.jcv.2007.07.016
  15. Lartey M, Edusei L et al.  Coinfection of Cutaneous Leishmaniasis and HIV Infection. Ghana Med J 2006; 40(3): 110-112
  16. Hesse IFA, Mensah A, Asante DK, Lartey M, Neequaye A.  Adult tetanus in Accra, why the high mortality?  An audit of clinical management of tetanus. W Afri J Med 2005; 25(2): 157-161
  17. Sagoe K W C, Lartey M, Agyei A A, Boamah I, Mingle J A A, Arens M.  Implications for antiretroviral therapy of dual HIV 1/HIV 2 serologic profiles in Accra, Ghana, West Africa. HIV AIDS Rev, 2005; 4(2): 24-27
  18. Adjei A A, Armah H, Rodrigues O, Renner L, Borketey P, Aryeh-Kumi P, Adiku T, Sifah E, Lartey M.  Cryptosporidium Spp., a Frequent Cause of Diarrhea among Children at the Korle-Bu Teaching Hospital, Accra, Ghana.  Jpn. J. Infect. Dis. 2004; 57: 216-219
  19. Hesse I F A, Mensah A, Asante D K, Lartey M and Neequaye A.  Characteristics of Adult tetanus in Accra. W Afri J Med 2003; 22(4): 291-294
  20. Adjei A, Lartey M, Adiku T K et al.  Cryptosporidium Oocysts in Ghanaian  AIDS patients with diarrhoea.  E. Afri. Med. J 2003; 80 (7): 369-72
  21. Botwe T A, Lartey M.  Trends in HIV Infections at the Korle Bu Teaching  Hospital.   Ghana Med. J 2003; 37(1): 3-6
  22. Lartey M. Skin Manifestations of HIV/AIDS in adults in Ghana. Ghana Med. J 2001; 35(1): 15 – 19.

 

Chapters in Books

  1. Lartey M, Common Medical Emergencies in Surgery. In Joe-Nat A Clegg-Lamptey, Henry K Aduful ed. Residents’ Companion in Surgical Practice. Ghana: Advocate Publishing Limited, 2008, pp 121-140
  2. Lartey M, Aduful H K:  Medical Conditions and Ward Emergencies in Surgery. In Joe-Nat A Clegg-Lamptey, Henry K Aduful ed. Residents’ Companion in Surgical Practice. Ghana: Advocate Publishing Limited, 2008, pp 141-151

Chapters in Monographs, Contributions to Treatment Guidelines etc

  1.     Lartey M., et al.  General/Internal Medicine in National Guidelines for clinical use    of blood and blood products in Ghana. WHO 2002; 18-22
  2.     Lartey Margaret et al, Beginnings of HIV and AIDS Care and Treatment in Ghana. The Korle-Bu Teaching    Hospital Experience. WHO 2007
  3.     Lartey Margaret et al, National HIV Drug Resistance Plan for Ghana, 2006-2010. National AIDS/STI Control Programme. Ghana Health Service 2007
  4.     Lartey Margaret et al, Guidelines for the Management of Opportunistic Infections and other Related HIV Diseases. National AIDS/STI Control Programme,  Ministry of Health. 2006
  5.     Lartey Margaret et al, Guidelines for Antiretroviral Therapy in Ghana. National AIDS/STI Control Programme. Ghana Health Service/Ministry of Health. 2005, Revised 2008