AREA(S) OF SPECIALIZATION
RESEARCH INTEREST
Prof. Awandare is the Director of West African Center for Cell Biology of Infectious Pathogens ( WACCBIP ). His research focuses on the pathogenesis of Plasmodium falciparum malaria in children. There are two main branches of investigations, namely the role of the host immune response on one hand, and the mechanisms used by the parasite to propagate itself and cause disease. From the perspective of the host, we have been investigating the production of inflammatory mediators and the relationship between genetic variation in innate immune response genes and susceptibility to severe malaria in children. Our research on the Plasmodium parasite is aimed at gaining a better understanding of the mechanisms used for invasion of red blood cells. Therefore, a substantial aspect of our research efforts focus on characterizing the sialic acid-independent pathways of invasion and identifying novel receptors and ligands involved.
SELECTED PUBLICATIONS
Adadey SM, Esoh KK, Quaye O, Amedofu GK, Awandare GA, Wonkam A (2020). GJB4 and GJC3 variants in non-syndromic hearing impairment in Ghana. Experimental Biology and Medicine (Maywood). Jun 11.153570220931053. doi: 10.117/1535370220931035.
Kinyanjui S, Fonn S, Kyobutungi C, Vicente-Crespo M, Bonfoh B, Ndungu T, Sewankambo NK, Djimde, AA, Gaye O, Chirwa T, Musenge E, Elliot A, Nakanjako D, Chibanda D, & Awandare G (2020). Enhancing science preparedness for health emergencies in Africa through research capacity building. BMJ Global Health;5:e003072. doi:10.1136/bmjgh-2020-003072
Amlabu WE, Antwi CA, Awandare G & Gwira TM (2020). Elucidating the possible mechanism of action of some pathogen box compounds against Leishmania donovani. PLoS Negl Trop Dis. 14(4):e0008188 doi:10.1371/journal.pntd.0008188
Aniweh Y, Nyarko PB, Charles-Chess E, Ansah F, Osier FHA, Quansah E, Thiam LG, Kamuyu G, Marsh K, Conway DJ, Tetteh KKA, Awandare GA (2020). Plasmodium falciparum Merozoite Associated Armadillo Protein (PfMAAP) is apically localized in free merozoites and antibodies are associated with reduced risk of malaria. Front. Immunol. 11:505. doi: 10.3389/fimmu.2020.00505
Amlabu E, Ilani P, Opoku G, Nyarko PB, Quansah E, Thiam LG, Anim M, Ayivor-Djanie R, Akuh O, Mensah-Brown H, Rayner JC and Awandare GA (2020). Molecular Characterization and Immuno-Reactivity Patterns of a Novel Plasmodium falciparum Armadillo-Type Repeat Protein, PfATRP. Frontiers in Cellular and Infection Microbiology, 10:114. doi: 10.3389/fcimb.2020.00114
Krampa FD, Aniweh Y, Kanyong P & Awandare GA (2020). Recent advances in the development of biosensors for malaria diagnosis. Sensors (Basel). 2020 Feb 1;20(3). pii: E799. doi: 10.3390/s20030799.
Deletsu SD, Maina EK, Quaye O, Ampofo WK, Awandare GA & Bonney EY (2020). High resistance to reverse transcriptase inhibitors among persons infected with human immunodeficiency virus type 1 subtype circulating recombinant form 02_AG in Ghana and on antiretroviral therapy. Medicine (Baltimore). 2020 Feb;99(7):e18777. doi: 10.1097/MD.0000000000018777
Aniweh Y, Suurbaar J, Morang’a CM, Nyarko PB, Wright KE, Kusi KA, Ansah F, Kyei-Baafour E, Quansah E, Asante J, Thiam LG, Higgins MK & Awandare GA (2020). Analysis of Plasmodium falciparum Rh2b deletion polymorphism across different transmission areas. Sci Rep 10, 1498, https://doi.org/10.1038/s41598-020-58300-3
Thiam LG, Aniweh Y, Quansah EB, Donkor JK, Gwira TM, Kusi KA, Niang M, Awandare GA (2020). Cell trace far-red is a suitable erythrocyte dye for multi-color Plasmodium falciparum invasion phenotyping assays. Experimental Biology and Medicine; 0: 1–10. DOI: 10.1177/1535370219897393
Nyarko PB, Tarr SJ, Aniweh Y, Stewart LB, Conway DJ & Awandare GA (2020). Investigating a Plasmodium falciparum erythrocyte invasion phenotype switch at the whole transcriptome level. Sci Rep 10, 245 doi:10.1038/s41598-019-56386-y
Adadey SM, Manyisa N, Mnika K, de Kock C, Nembaware V, Quaye O, Amedofu GK, Awandare GA, Wonkam A (2019). GJB2 and GJB6 Mutations in Non-Syndromic Childhood Hearing Impairment in Ghana. Front. Genet.,https://doi.org/10.3389/fgene.2019.00841
Mensah-Brown HE, Aspeling-Jones H, Delimini RK, Asante KP, Amlabu E, Bah SY, Beeson JG, Wright GJ, Conway DJ, & Awandare GA (2019). Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against Plasmodium falciparum in Culture. Open Forum Infectious Diseases, 6:7, ofz254, https://doi.org/10.1093/ofid/ofz254
Kotey E, Lukosaityte D, Quaye O, Ampofo W, Awandare G, Iqbal M (2019). Current and Novel Approaches in Influenza Management. Vaccines (Basel), 7(2). pii: E53. doi: 10.3390/vaccines7020053
Anabire NG, Aryee PA, Abdul-Karim A, Quaye O, Awandare GA, Helegbe GK (2019). Impact of malaria and hepatitis B co-infection on clinical and cytokine profiles among pregnant women. PloS one, 14(4), e0215550
Aniweh Y, Nyarko PB, Quansah E, Thiam LG, Awandare GA (2019). SMIM1 at a glance; discovery, genetic basis, recent progress and perspectives. Parasite Epidemiol Control 5:e00101. doi: 10.1016/j.parepi.2019.e00101
Sangare M, Toure HB, Toure A, Karembe A, Dolo H, Coulibaly YI, Kouyate M, Traore K, Diakité SA, Coulibaly S, Togora A, Guinto CO, Awandare GA, Doumbia S, Diakite M, Geschwind DH. (2019). Validation of two parent-reported autism spectrum disorders screening tools M-CHAT-R and SCQ in Bamako, Mali. eNeurologicalSci 15:100188. doi: 10.1016/j.ensci.2019.100188.
Kengne-Ouafo JA, Sutherland CJ, Binka F, Awandare GA, Urban BC and Dinko B. (2019). Immune Responses to the Sexual Stages of Plasmodium falciparum Parasites. Front. Immunol., 11 February 2019
Nsoh GA, Aryee PA, Abdul-Karim A, Abdulai IB, Quaye O, Awandare GA and Helegbe GK. (2019). Prevalence of malaria and hepatitis B among pregnant women in Northern Ghana: Comparing RDTs with PCR. PLos ONE 14(2):e0210365
Tarr SJ, Diaz-Ingelmo O, Stewart LB, Hocking SE, Murray L, Duffy CW, Otto TD, Chappel L, Rayner JC, Awandare GA, and Conway DJ (2018). Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of malaria parasite Plasmodium falciparum, BMC Genomics 2018 19:894
Bah, S. Y., Morang’a, C. M., Kengne-Ouafo, J. A., Amenga–Etego, L., & Awandare, G. A. (2018). Highlights on the Application of Genomics and Bioinformatics in the Fight Against Infectious Diseases: Challenges and Opportunities in Africa. Front. Genet. 9:575. doi: 10.3389/fgene.2018.00575
Oyebola KM, Aina OO, Idowu ET, Olukosi YA, Ajibaye OS, Otubanjo OA, Awolola TS, Awandare GA, Amambua-Ngwa A. (2018), A barcode of multilocus nuclear DNA identifies genetic relatedness in pre- and post-Artemether/Lumefantrine treated Plasmodium falciparum in Nigeria, BMC Infectious Diseases 2018 18:392 https://doi.org/10.1186/s12879-018-3314-3
Duffy CW, Amambua-Ngwa A, Ahouidi AD, Diakite M, Awandare GA, Ba H, Tarr SJ, Murray L, Stewart LB, D’Allessandro U,Otto TD, Kwiatkowski DP, Conway DJ. (2018). Multi-population genomic analysis of malaria parasites indicates local selection and differentiation at the gdv1 locus regulating sexual development, Scientific Report 8, Article number:15763(2018)
Osei M, Ansah F, Matrevi SA, Asante KP, Awandare GA, Quarshie NB, et al. (2018) Amplification of GTP-cyclohydrolase 1 gene in Plasmodium falciparum isolates with the quadruple mutant of dihydrofolate reductase and dihydropteroate synthase genes in Ghana. Plos ONE 13(9):e0204871. https://doi.org/10.1371/journal.pone.0204871
Amoako, N., Duodu, S., Dennis, F. E., Bonney, J. H. K., Asante, K. P., Ameh, J., Mosi, L., Hayashi, T., Agbosu, E. E., Pratt, D., Operario, D. J., Fields, B., Liu, J., Houpt, E. R., Armah, G. E., Stoler, J. and Awandare, G. A. (2018). Detection of dengue virus among children with suspected malaria, Accra, Ghana. Emerging Infectious Diseases. 24(8):1544-1547. doi: 10.3201/eid2408.180341
Hogarh, J. N., Agyekum, T. P., Bempah, C. K., Owusu-Ansah, E. D. J., Avicor, S. W., Awandare, G. A., Fobil, J. N., & Obiri-Danso, K (2018). Environmental health risks and benefits of the use of mosquito coils as malaria prevention and control strategy. Malaria Journal. 17(1):265. doi: 10.1186/s12936-018-2412-4.
Awandare, G.A., Nyarko, P. B., Aniweh, Y., Ayivor-Djanie, R., & Stoute, J. A. (2018). Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture. Scientific Reports. 8(1):5782. doi: 10.1038/s41598-018-24218-0.
Abugri, J., Ansah,, Asante, K. P., Opoku, C. N., Amenga-Etego, L. A. & Awandare, G. A. (2018). Prevalence of chloroquine and antifolate drug resistance alleles in Plasmodium falciparum clinical isolates from three areas in Ghana. African Academy of Sciences Open Research. DOI: 10.12688/aasopenres.12825.1
Kanyong, P., Krampa, F., Aniweh, Y. & Awandare, G. (2018). Polydopamine-functionalized graphene nanoplatelet smart conducting electrode for bio-sensing applications. Arabian Journal of Chemistry. In press. DOI: 10.1016/j.arabjc.2018.01.001.
Thomford, N. E., Dzobo, K., Yao N. A., Chimusa, E., Evans, J., Okai, E., Kruszka, P., Muenke, M., Awandare, G., Wonkam, A., & Dandara, C (2018). Genomics and epigenomics of congenital heart defects: expert review and lessons learned in Africa. OMICS: A Journal of Integrative Biology. 2018 May;22(5):301-321. doi: 10.1089/omi.2018.0033
Essel, T. Y. A., Koomson, A., Seniagya, M. O., Cobbold, G. P., Kwofie, S. K., Asimeng, B. O., Arthur, P. K., Awandare, G., Tiburu, E. K. (2018). Chitosan composites synthesized using acetic acid and tetraethylorthosilicate respond differently to methylene blue adsorption. Polymers 10, 466; doi:10.3390/polym10050466
Oyebola, K. Oyebola, K. M., Aina, O. O., Bah, M. M., Ajibaye, S., Correa, S., Awandare, G. A., & Amambua-Ngwa, A. (2018). Assessing naturally acquired immune response and malaria treatment outcomes in Lagos, Nigeria. AAS Open Research, 1.
Dinko, B., Amakpa, E., Kweku, M., AMoah, P., Tampuori, J., Adjuik, M., Awandare, G. A., & Deitsch, K. W., (2018). Plasmodium falciparum malaria cases detected for prompt treatment by rapid diagnostic tests in the Ho Teaching Hosipital for the Volta Region of Ghana. Paraiste Epidemiology and Control 3(3):e00072. doi: 10.1016/j.parepi.2018.300072.
Anabire, N. G., Aryee, P. A., Addo, F., Anaba, F., Kanwugu, O. N., Ankra, J, Awandare, G. A., Helegbe, G. K., (2018) , Evaluation of hematological indices of childhood illnesses in Tamale Metropolics of Ghana, Journal of Clinical Laboratory Analysis, 2018, June 3:e22582, doi: 10.1002/jcla.22582
Dinko, B., Ansah, F., Agyare-Kwabi, C., Tagboto, S., Amoah, L. E., Urban, B. C., Sutherland, C. J., Awandare, G. A., Williamson, K. C., Binka, F. N., Deitsch, K. W., (2018), Gametocyte Development and Carriage in Ghanaian Individuals with Uncomplicated Plasmodium falciparum Malaria, The American Journal of Tropical Medicine and Hygiene, DOI: 10.4269/ajtmh.18-0077.
Amlabu, E., Mensah-Brown, H., Nyarko, P. B., Akuh, OL, Opoku, G., Ilani, P., Oyagbenro, R., Asiedu, K., Aniweh,, Y., Awandare, G. A., (2018), Functional Characterization of Plasmodium falciparum Surface Related Antigen(PfSRA) as a Potential Blood-Stage Vaccine Target, Journal of Infectious Diseases , DOI: 10.1093/infdis/jiy22.
Awandare, G. A., Nyarko, P. B., Aniweh, Y. , Ayivor-Djanie, R., Stoute , J. A., (2018). Plasmodium falciparum strains spontaneously switch invasion phenotype in suspension culture. Scientific Report 8(1),5782. DOI: 10.1038/s41598-018-24218-0
Ademolue, T. W. and Awandare, G. A., (2017). Evaluating antidisease immunity to malaria and implications for vaccine design, Immunology, The Journal of cells, molecules, systems and technologies, November 2017, DOI: 10.1111/imm.12877
Adadey, S. M., Awandare, G. A. , Amedofu, G. K., Wonkam, A., (2017). Public Health Burden of Hearing Impairment and the Promise of Genomics and Environmental Research: A Case Study in Ghana, Africa, OMICS:Journal of Integrative Biology, November 2017, Vol. 21, No. 11:638:646
Chirawurah, D. J., Ansah, F., Nyarko, P. B., Duodu, S., Aniweh, Y., Awandare, G. A., (2017). Antimalarial activity of Malaria Box compounds against Plasmodium falciparum clinical isolates, International Journal for Parasitology : Drugs and Drug Resistance, Volume 7, Issue 3, December 2017, DOI: 10.1016/j.ijpddr.2027.10.005, Pages 399-406
Kusi, K. A., Manu, E. A., Gwira, T. M., Kyei-Baafour, E., Dickson, E. K., Amponsah, J. A., Remarque E. J., Faber, B. W., Kocken, C. H. M., Dodoo, D., Gyan, B. A., Awandare, G. A., Atuguba, F., Oduro A. R., Koram, K. A. (2017). Variations in the quality of malaria-specific antibodies with transmission intensity in a seasonal malaria transmission area of Northern Ghana. PLoS One. 12(9):e0185303.doi: 10.1371/journal.pone.0185303
Krampa, F. D., Aniweh, Y., Awandare, G. A., Kanyong P., ( 2017). Recent Progress in the Development of Diagnostic Tests for Malaria, Diagnostics 2017, 7(3), 54; doi:10.3390/diagnostics7030054
Kanyong P., Krampa, F. D., Aniweh, Y., Awandare, G. A., (2017). Enzyme-based amperometric galactose biosensors: a review, Microchim Acta, DOI:10.1007/s00604-017-2465-z
Anderson, D. E., Balapangu, S., Fleischer, H. N. A., Viade, R. A., Krampa, F. D., Kanyong, P., Awandare, G. A., Tiburu, E. K. (2017). Investigating the Influence of Temperature on the Kaolinite-Base Synthesis of Zeolite and Urease Immobilization for the Potential Fabrication of Electrochemical Urea Biosensors, Sensors 2017, 17(8), 1831; doi:10.3390/s17081831
Cissé, M., Awandare, G. A., Somé, F. A., Hayette, M. P., Guiguemdé, R. T. (2017). High concordance of Pfdhfr and Pfdhps genotypes between matched peripheral and placental isolates of delivered women in Bobo-Dioulasso, Burkina Faso, Annals of Parasitology 2017, 63(2), 111–116 doi: 10.17420/ap6302.93
Krampa, D. F., Aniweh, Y., Awandare, G. A., Kanyong, P., (2017). Disposable Amperometric Sensor Based on High-Performance PEDOT:PSS / Ionic Liquid Nanocomposite Thin Film-Modified Screen-Printed Electrode for the Analysis of Catechol in Natural Water Samples, MDPI 17(18), 1716; doi:10.3390/s17081716
Bakari, S. M., Ofori, J. A., Kusi, K. A., Aning, G. K., Awandare, G. A., Carrington, M., Gwira, T. M. (2017). Serum biochemical parameters and cytokine profiles associated with natural African trypanosome infections in cattle Parasites & Vectors 2017 10:312 DOI: 10.1186/s13071-017-2255-9
Ademolue, T.W., Aniweh, Y., Kusi, K. A. & Awandare , G.A. (2017). Patterns of inflammatory responses and parasite tolerance vary with malaria transmission intensity. Malaria Journal , 16:145
Azumah, B. K., Addo , P. G., Dodoo , A., Awandare, G. A, Mosi, L., Boakye, D. A., et al (2017). Experimental demonstration of the possible role of Acanthamoeba polyphaga in the infection and disease progression in Buruli Ulcer (BU) using ICR mice. PLos ONE 12(3): e0172843. DOI
Mensah Brown, H. E., Abugri, J., Asante, K. P., Dwomoh, D., Dosoo, D., Atuguba, F., Conway, D. J., & Awandare, G. A. (2017). Assessing the impact of differences in malaria transmission intensity on clinical and haematological indices in children with malaria. Malaria Journal, 16:96, DOI 10.1186/s12936-017-1745-8, 1 March 2017
Ademolue, T., Amodu, O., & Awandare, G. A. (2017). Sickle cell trait is associated with controlled levels of heme and mild pro-inflammatory response during acute malaria infection. Clinical & Experimental Immunology, DOI: 10.1111/cei.12936
Cisse, M., Awandare, G. A., Soulama, A., Tinto, H., Hayette, M. P., & Guiguemdé R. T. (2017). Recent uptake of intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine is associated with increased prevalence of Pfdhfr mutations in Bobo‑Dioulasso, Burkina Faso. Malaria Journal; DOI 10.1186/s12936-017-1695-1
Sam-Agudu N. A., Paintsil , E. , Aliyu ,M. H., Kwara, A., Ogunsola ,F., Afrane ,Y. A., Onoka ,C., Awandare ,G. A., Amponsah, G., Cornelius ,L. J., Mendy ,G., Sturke, R., Ghansah, A., Siberry & G. K., Ezeanolue E. E. (2016). Building Sustainable Local Capacity for Global Health Research in West Africa. Annals of Global Health, 82 (6). DOI:10.1016/j.aogh.2016.10.011
Amato, R., Miotto, O., Woodrow, C.J., Almagro-Garcia, J., Sinha I., Campino S., Mead, D., Drury, E., Kekre, M., Sanders, M., Amambua-Ngwa, A., Amaratunga, C., Amenga-Etego, L., Andrianaranjaka, V., Apinjoh, T., Ashley, E., Auburn, S., Awandare, G.A., Baraka, V., Barry, A.,Boni, M.F., Borrmann, S., Bousema, T., Branch, O., Bull, P.C., Chotivanich, K., Conway, D.J., Craig, A., Day, N.P., Djimdé, A., Dolecek, C., Dondorp, A.M., Drakeley, C., Duffy, P., Echeverry, D.F., Egwang, T.G., Fairhurst, R.M., Faiz, A., Fanello, C.I., Hien, T.T., Hodgson, A., Imwong, M., Ishengoma, D., Lim, P., Lon, C., Marfurt, J., Marsh, K., Mayxay, M., Michon, P., Mobegi, V., Mokuolu, O.A., Montgomery, J., Mueller, I., Kyaw,M.P., Newton, P.N., Nosten, F., Noviyanti, R., Nzila, A., Ocholla, H., Oduro, A., Onyamboko, M., Ouedraogo, J.-B., Phyo, A.P.P., Plowe, C., Price, R.N., Pukrittayakamee, S., Randrianarivelojosia, M., Ringwald, P., Ruiz, L., Saunders, D., Shayo, A., Siba, P., Takala-Harrison, S., Thanh, T.-N.N., Thathy, V., Verra, F., Wendler, J., White, N.J., Ye, H., Cornelius, V.J., Giacomantonio, R., Muddyman, D., Henrichs, C., Malangone, C., Jyothi, D., Pearson, R.D., Rayner, J.C., McVean, G., Rockett, K.A., Miles, A., Vauterin, P., Jeffery, B., Manske, M., Stalker, J., Macinnis, B., Kwiatkowski, D.P.,(2016). Genomic epidemiology of artemisinin resistant malaria, eLife; Volume 5, Issue Article number e08714
Stoler, J. & Awandare, G.A. (2016). Febrile illness diagnostics and the malaria-industrial complex: A socio-environmental perspective. BMC Infectious Diseases; Volume 16, Issue 1, 17 November 2016, Article number 683.
Ahouidi, A. D., Amambua-Ngwa, A., Awandare , G.A., Bei, A.K., Conway, D.J., Diakite, M., Duraisingh, M.T., Rayner, J.C., Zenonos, Z. A., (2016). Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN), Trends in Parasitoloty; Volume 32, Issue 4, Pages 274-283.
Stoler , J., Delimini, R. K., Bonney, K. J. H., Oduro, A. R., Owusu-Agyei, S., Fobil J.N.,& Awandare, G. A. (2015). Evidence of recent Dengue exposure among malaria parasite-positive children in three urban centers in Ghana. Am J Trop Med Hyg,, 92(3) , 497-500.
The West African Merozoite Invasion Network (WAMIN): (in alphabetical order): Ahouidi A. D., Amambua-Ngwa A., Awandare, G. A., Bei A. K., Conway D. J., Diakite M., Duraisingh M. T., Rayner J. C., & Zenonos Z. A. Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity (2015). Trends Parasitology. 2015 Dec 22. pii: S1471-4922(15)00253-6. doi: 10.1016/j.pt.2015.11.009
Duffy, C. W., Assefa, S. A., MacInnis, B., Abugri, J., Amoako, N., Owusu-Agyei, S., Anyorigiya, T., Kwiatkowski, D. P., Conway, D. J. & Awandare, G. A. (2015). Comparison of genomic signatures of selection on Plasmodium falciparum between different regions of a country with high malaria endemicity. BMC Genomics. 16:527.
Bowyer, P. W., Stewart, L. B., Aspeling-Jones, H., Mensah-Brown, H. E., Ahouidi, A. D., Amambua-Ngwa, A., Awandare, G. A., & Conway, D. J. (2015). Variation in Plasmodium falciparum Erythrocyte Invasion Phenotypes and Merozoite Ligand Gene Expression across Different Populations in Areas of Malaria Endemicity. Infection and Immunity. 83(6):2575-82.
Mensah-Brown, H. E., Amoako, N., Abugri, J., Stewart, L. B., Agongo, G., Dickson, E. K., Ofori, M. F., Stoute, J. A., Conway, D. J., & Awandare, G. A. (2015). Analysis of Erythrocyte Invasion Mechanisms of Plasmodium falciparum Clinical Isolates Across 3 Malaria-Endemic Areas in Ghana. Journal of Infectious Diseases. 212(8):1288-97
Amoako, N., Asante, K. P., Adjei, G., Awandare, G. A., Bimi, L., & Owusu-Agyei, S. (2014). Associations between Red Cell Polymorphisms and Plasmodium falciparum Infection in the Middle Belt of Ghana. PLoS One. 9(12).
Stoler, J.,al Dashti, R.A., Anto,F., Fobil, J. N., & Awandare, G.A. (2014). Deconstructing "malaria": West Africa as the next front for dengue fever surveillance and control. Acta Trop., 134(1), 58 - 65.
Awandare, G. A., & Stoute, J. A. (2014). Malaria parasites in blood red cell invasion mechanisms (Parasites, Pathogens and Immunochemistry). In: L. N. A. Okine, W. S. K. Gbewonyo, & M. Nyako (Eds.), Molecular approaches to understanding life and disease: a reader from Department of Biochemistry, Cell and Molecular Biology University of Ghana (pp. 119 – 134). Tema: Digibooks Ghana Ltd.
Awandare, G. A., & Perkins, D. J. (2014). Innate Immune response to malaria: the role of cytokine genes (Parasites, Pathogens and Immunochemistry). In: L. N. A. Okine, W. S. K. Gbewonyo, & M. Nyako (Eds.), Molecular approaches to understanding life and disease: a reader from Department of Biochemistry, Cell and Molecular Biology University of Ghana (pp. 163 – 180). Tema: Digibooks Ghana Ltd.
Boeuf, P. S., Loizon, S., Awandare, G. A., Tetteh, J. K., Addae, M. M., Adjei, G. O., Goka, B., Kurtzhals, J. A., Puijalon, O., Hviid, L., Akanmori, B. D., & Behr, C. (2012). Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia. Malaria Journal. 11(1):253.
Awandare, G. A., Kempaiah, P., Ochiel, D. O., Piazza, P., Christopher, C.K., & Perkins, D. J. (2011). Mechanisms of erythropoiesis inhibition by malarial pigment and malaria-induced proinflammatory mediators in an in vitro model. American Journal of Hematology. 86(2):155-62.
Awandare, G. A., Spadafora, C., Moch, K. J., Dutta, S., Haynes, J. D., & Stoute, J. A. (2011). Plasmodium falciparum field isolates use complement receptor 1 (CR1) as a receptor for invasion of erythrocytes. Molecular & Biochemical Parasitology. 177(1):57-60.
Spadafora, C., Awandare, G. A., Kopydlowski, K. M., Czege, J., Moch, K. J., Finberg, W. R., Tsokos, G. C. & Stoute.J. A. (2010). Complement receptor 1 is a sialic acid independent erythrocyte receptor of Plasmodium falciparum. PLoS Pathogens. 6(6).
Awandare, G. A., Martinson, J. J., Were, T., Ouma, T, Davenport, G. C., Ong’echa, J. M., Wang, W. K., Leng, L., Ferrell, R. E., Bucala, R., & Perkins, D. J. (2009). Macrophage migration inhibitory factor (MIF) promoter polymorphisms and susceptibility to severe malarial anemia. Journal of Infectious Diseases. 200(4): 629-637.
Keller, C. C., Ouma, C., Ouma, Y., Awandare, G. A., Davenport, G. C., Were, T., Hittner, J. B., Vulule, J. M., Ong’echa, J. M., & Perkins, D. J. (2009). Suppression of a novel hematopoietic mediator in children with severe malarial anemia. Infection and Immunity. 77(9):3864-71.
Were, T., Davenport, G. C., Ouma, Y. E., Hittner, B. J., Awandare, G. A., Otieno, M. F., Ouma, C., Orago, A. S., Vulule, J. M., Ong’echa, J. M., & Perkins, D. J. (2009). Naturally acquired hemozoin by monocytes promotes suppression of RANTES in children with malarial anemia through an IL-10-dependent mechanism. Microbes and Infection. 11(8-9):811-9.
Ouma, C., Davenport, G. C., Awandare, G. A., Keller, C. C., Were, T., Otieno, M. F., Vulule, J. M., Martinson, J., Ong’echa, J. M., Ferrell, R. E., & Perkins, D. J. (2008). Polymorphic Variability in the Interleukin (IL)-1beta Promoter Conditions Susceptibility to Severe Malarial Anemia and Functional Changes in IL-1beta Production. Journal of Infectious Diseases. 198(8):1219-26.
Ong’echa, J. M, Remo, A. M., Kristoff, J, Hittner, J. B., Were, T., Ouma, C., Otieno, R. O., Vulule, J. M, Keller, C. C., Awandare, G. A., & Perkins, D. J. (2008). Increased circulating interleukin (IL)-23 in children with malarial anemia: in vivo and in vitro relationship with co-regulatory cytokines IL-12 and IL-10. Clinical Immunology. 126(2):211-21.
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