BCMB 608 : Signal Transduction

This is an advanced course on cell signaling designed to give students insights into the underlying molecular mechanisms and current trends in signal transduction research. The format includes lectures, presentations of original literature by students, and discussions of selected papers with emphasis on experimental approaches and results. Major topics covered include: Types of signaling molecules; Cell Surface and nuclear receptors; Monomeric and heterotrimeric guanine nucleotide binding proteins; Effectors and regulators of receptor tyrosine kinase signaling pathways, G-protein coupled receptor signaling; Cytokine receptor signaling; Signaling through ion channels; Receptor transactivation and Crosstalk