Dorcas Osei-Safo [M.Phil, Ph.D (Ghana)]

ACADEMIC QUALIFICATIONS

• Ph. D.     31/12/1999; Chemistry; Department of Chemistry, University of Ghana, Legon

• B. Sc.  08/08/1991; Chemistry with Biochemistry; Department of Chemistry, University of Ghana, Legon

RESEARCH INTEREST

• Isolation and characterization of bioactive compounds from medicinal plants

• Application of quality assurance methods to antimalarial drugs   .

AREA OF SPECIALIZATION

• Natural Product Chemistry

SELECTED PUBLICATIONS

1. C. Awortwe, Dorcas Osei-Safo, I. J. Asiedu-Gyekye and A. C. Sackeyfio (2013). Antiinflammatory

activity of Taraxacum officinale leaves in ovalbumin-sensitized guinea-pigs.

International Journal of Pharmacy and Pharmaceutical Sciences, 5(2), 628-63.

2. S.K. Amponsah, K.A. Bugyei, D. Osei-Safo,  F.K. Addai, G. Asare, A. Tsegah, J. Baah, M.

 Ofori, and B. Gyan, (2012). In Vitro Activity of extract and fractions of natural Cocoa powder

on Plasmodium falciparum and inflammatory response mechanisms in malaria. Journal of

Medicinal Food, 15(5):476-82. DOI: 10.1089/jmf.2011.0220. Epub 2012 Jan 16.

3. C. Awortwe, A. C. Sackeyfio, Dorcas Osei-Safo, K. A. Bugyei  and I. J. Asiedu-Gyekye

(2011). Dual effect of Taraxacum officinale leaves: Anticholinergic and inhibitory effect on

inflammatory cells in ovalbumin-sensitized guinea-pigs. African Journal of Pharmacy and

Pharmacology, 5(23), 2613-2619. DOI: 10.5897/AJPP11.616  

4. Osei-Safo, D., Addae-Mensah, I., Garneau, F-X and Koumaglo, H. K., (2010). A comparative

study of the antimicrobial activity of the leaf essential oils of chemo-varieties of Clausena

anisata (Willd.) Hook. F. Benth. Industrial Crops & Products, 32 (3), 634-638. (DOI:10.1016/j.indcrop.2010.07.016).

5. Osei-Safo, D., Harrison, J.J.E.K. and Addae-Mensah, I., (2010). “Validation and

application of quality assurance methods developed for artemisinin-based antimalarial

drugs to assess the quality of a selection of such drugs distributed in Accra, Ghana”.

African Journal of Pharmaceutical Sciences and Pharmacy, 1:1, 1-26.

6. Osei-Safo, D., Chama, M. A., Addae-Mensah, I., and Waibel, R., (2009). Hispidulin and

other constituents of Scoparia dulcis Linn. Journal of Science and Technology (KNUST), 29

(2), 7-15.

7. Osei-Safo, D., Chama, M. A., Addae-Mensah, I., Waibel, R., Asomaning, W. A., Oppong, I.

V. (2008). Dichapetalin M from Dichapetalum madagascariense. Phytochemistry Letters 1,

147-150.

8. Osei-Safo, D., Addae-Mensah, I. Asomaning, W. A., Garneau, F-X, Koumaglo, K. H.,

Oppong I. V. (2002). Insecticidal properties of Clausena anisata. 5e

 Colloque ProduitsNaturels d’Origine Vegetale.  Actes du Colloque Sainte-Foy (Proceedings of the 5th

Colloquium on Natural Products of Vegetable Origin), pp179-186.

 9. Osei-Safo, D., Addae-Mensah, I., Asomaning, W. A., Garneau, F-X, Koumaglo, K. H.,

Oppong I. V. (2002). Coumarins of the Chemovarieties of Clausena anisata. 5

ColloqueProduits Naturels d’Origine Vegetale.  Actes du Colloque Sainte-Foy (Proceedings of the 5th

Colloquium on Natural Products of Vegetable Origin), pp 187 -192.

10. Garneau, F-X, Pichette, A., Gagnon, H., Jean, F-I. Addae-Mensah, I., Osei-Safo, D.,

Asomaning, W. A., Oteng-Yeboah, A., Moudachirou,M., Koumaglo, K. H. (2000). (E)- and

(Z)- Foeniculin, constituents of the leaf oil of a New Chemovariety of Clausena anisata. J.

Essential Oil Research, 12, 757-762.